Early Short-Course Corticosteroids in Hospitalized Patients With COVID-19

• Published in: Clinical infectious diseases Vol. 71; no. 16; pp. 2114 - 2120
• Main Authors: Fadel, Raef, Morrison, Austin R, Vahia, Amit, Smith, Zachary R, Chaudhry, Zohra, Bhargava, Pallavi, Miller, Joseph, Kenney, Rachel M, Alangaden, George, Ramesh, Mayur S
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 19.11.2020
• Subjects: Adrenal Cortex Hormones - administration & dosage; Adrenal Cortex Hormones - therapeutic use; and Commentaries; COVID-19 Drug Treatment; Female; Hospitalization - statistics & numerical data; Humans; Male; Methylprednisolone - administration & dosage; Methylprednisolone - therapeutic use; Middle Aged; Multicenter Studies as Topic; COVID-19; coronavirus; Corticosteroids; outcomes; SARS-COV-2

Abstract Background There is no proven antiviral or immunomodulatory therapy for coronavirus disease 2019 (COVID-19). The disease progression associated with the proinflammatory host response prompted us to examine the role of early corticosteroid therapy in patients with moderate to severe COVID-19...