Effects of an Eight Week Very Low-Calorie Ketogenic Diet (VLCKD) on White Blood Cell and Platelet Counts in Relation to Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Subjects with Overweight and Obesity

• Published in: Nutrients Vol. 15; no. 20; p. 4468
• Main Authors: De Nucci, Sara, Bonfiglio, Caterina, Donvito, Rosanna, Di Chito, Martina, Cerabino, Nicole, Rinaldi, Roberta, Sila, Annamaria, Shahini, Endrit, Giannuzzi, Vito, Pesole, Pasqua Letizia, Coletta, Sergio, Lanzilotta, Elsa, Piazzolla, Giuseppina, Cozzolongo, Raffaele, Giannelli, Gianluigi, De Pergola, Giovanni
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.10.2023; MDPI
• Subjects: Adolescent; Adult; Alcohol; bioelectrical impedance; Biomarkers; Blood; blood glucose; Blood platelets; blood pressure; Body mass index; Calories; Cardiovascular disease; Cholesterol; Diabetes; Diet; Diet, Ketogenic; drug therapy; elasticity imaging techniques; Fatty liver; Fatty Liver - complications; Female; fibrosis; High density lipoprotein; high density lipoprotein cholesterol; Humans; Inflammation; Inflammation - complications; insulin; Insulin resistance; ketogenic diet; leukocytes; Leukocytes - metabolism; liver; Liver cirrhosis; Liver Cirrhosis - complications; Liver diseases; low density lipoprotein cholesterol; Male; Metabolic syndrome; Middle Aged; Nutrition research; nutritional intervention; Obesity; Obesity - metabolism; Overweight; Overweight - complications; Patients; Platelet Count; Proteins; Risk factors; waist circumference; Weight control; weight loss; Womens health; Young Adult; Italy; non-alcoholic fatty liver disease (NAFLD); metabolic dysfunction-associated steatotic liver disease (MASLD); platelets (PLT); transient elastography (FibroScan); very low-calorie ketogenic diet (VLCKD); insulin resistance; obesity; white blood cell (WBC)

Obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) are frequently associated conditions characterized by low-grade inflammation. Very low-calorie ketogenic diet (VLCKD) strategies are commonly used to simultaneously obtain weight loss and an improvement of liver steatosis....