Effect of the consumption of hesperidin in orange juice on the transcriptomic profile of subjects with elevated blood pressure and stage 1 hypertension: A randomized controlled trial (CITRUS study) - Pla-Pagà, Laura; Valls, Rosa M.; Pedret, Anna; Calderón-Pérez, Lorena; Llauradó, Elisabet; Companys, Judit; Domenech-Coca, Cristina; Canela, Nuria; del Bas, Josep M.; Caimari, Antoni; Puiggròs, Francesc; MI, Covas; et al. (Clinical nutrition (Edinburgh, Scotland), 2021)
Keywords: 3-Hydroxysteroid Dehydrogenases - metabolism; Adult; Blood Pressure - genetics; Citrus; Citrus sinensis; clinical nutrition; Double-Blind Method; Down-Regulation; Female; Fruit and Vegetable Juices; Gene Expression - drug effects; genes; Hesperidin; Hesperidin - administration & dosage; Hesperidin - pharmacology; Humans; hypertension; Hypertension - genetics; Hypertensive subjects; inflammation; insulin resistance; Leukocytes, Mononuclear - metabolism; Male; mechanism of action; Middle Aged; Orange juice; PBMCs; Plasma; randomized clinical trials; Selenium-Binding Proteins - metabolism; systolic blood pressure; Transcriptome - drug effects; Transcriptomic analysis; transcriptomics; SBP; Plasma; CD; EOJ; LncRNA; Transcriptomic analysis; PBMCs; CVD; Hypertensive subjects; DBP; Orange juice; IPA; OJ; Hesperidin; CVDR; CVDRFs