Effect of variation in ITGAE on risk of sarcoidosis, CD103 expression, and chest radiography

Abstract The integrin αE β7 is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common single nucleotide polymorphisms spanning ITGAE , the gene encoding the αE (CD103) unit, were genotyped in 556 sarcoidosis patients and 465 controls...

Full description

Saved in:
Bibliographic Details
Published inClinical immunology (Orlando, Fla.) Vol. 133; no. 1; pp. 117 - 125
Main Authors Heron, M, Grutters, J.C, Van Moorsel, C.H.M, Ruven, H.J.T, Kazemier, K.M, Claessen, A.M.E, Van den Bosch, J.M.M
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.10.2009
Subjects
Alleles
Allergy and Immunology
Antigens, CD - genetics
Antigens, CD - immunology
Bronchoalveolar Lavage Fluid - immunology
CD103
CD4-Positive T-Lymphocytes - immunology
CD4-Positive T-Lymphocytes - metabolism
CD8-Positive T-Lymphocytes - immunology
CD8-Positive T-Lymphocytes - metabolism
Epithelium
Exons - genetics
Exons - immunology
Female
Fibrosis
Gene Frequency - genetics
Gene Frequency - immunology
Genetic Predisposition to Disease
Genotype
Humans
Integrin alpha Chains - genetics
Integrin alpha Chains - immunology
Introns - genetics
Introns - immunology
ITGAE
Linkage Disequilibrium - genetics
Linkage Disequilibrium - immunology
Male
Polymorphism, Single Nucleotide
Promoter Regions, Genetic - genetics
Promoter Regions, Genetic - immunology
Radiography
Sarcoidosis
Sarcoidosis - diagnostic imaging
Sarcoidosis - genetics
Sarcoidosis - immunology
Single nuclear polymorphism
Single nuclear polymorphism
ITGAE
Sarcoidosis
CD103
Epithelium
Fibrosis
Online AccessGet full text

Cover

Abstract Abstract The integrin αE β7 is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common single nucleotide polymorphisms spanning ITGAE , the gene encoding the αE (CD103) unit, were genotyped in 556 sarcoidosis patients and 465 controls. The − 1088 A/G polymorphism was associated with sarcoidosis ( P = 0.004). An increased risk of disease was found for homozygous carriers of the A allele vs. carriers of the G allele ( P = 0.001, odds ratio = 1.63 [1.22–2.17]). Analysis of lymphocytes from bronchoalveolar lavage and in vitro functional tests showed higher percentages of CD103+CD4+ T cells for the sarcoidosis risk genotype. Radiographic staging at disease outcome revealed prevalence of − 1088 AA genotype in patients with fibrosis ( P = 0.01). A higher proportion of CD103+CD4+ T cells and ITGAE − 1088 AA genotype might be associated with fibrosis formation in pulmonary sarcoidosis.
AbstractList The integrin α Eβ 7 is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common single nucleotide polymorphisms spanning ITGAE, the gene encoding the α E (CD103) unit, were genotyped in 556 sarcoidosis patients and 465 controls. The − 1088 A/G polymorphism was associated with sarcoidosis ( P = 0.004). An increased risk of disease was found for homozygous carriers of the A allele vs. carriers of the G allele ( P = 0.001, odds ratio = 1.63 [1.22–2.17]). Analysis of lymphocytes from bronchoalveolar lavage and in vitro functional tests showed higher percentages of CD103+CD4+ T cells for the sarcoidosis risk genotype. Radiographic staging at disease outcome revealed prevalence of − 1088 AA genotype in patients with fibrosis ( P = 0.01). A higher proportion of CD103+CD4+ T cells and ITGAE − 1088 AA genotype might be associated with fibrosis formation in pulmonary sarcoidosis.
The integrin alpha(E)beta(7) is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common single nucleotide polymorphisms spanning ITGAE, the gene encoding the alpha(E) (CD103) unit, were genotyped in 556 sarcoidosis patients and 465 controls. The -1088 A/G polymorphism was associated with sarcoidosis (P=0.004). An increased risk of disease was found for homozygous carriers of the A allele vs. carriers of the G allele (P=0.001, odds ratio=1.63 [1.22-2.17]). Analysis of lymphocytes from bronchoalveolar lavage and in vitro functional tests showed higher percentages of CD103+CD4+ T cells for the sarcoidosis risk genotype. Radiographic staging at disease outcome revealed prevalence of -1088 AA genotype in patients with fibrosis (P=0.01). A higher proportion of CD103+CD4+ T cells and ITGAE -1088 AA genotype might be associated with fibrosis formation in pulmonary sarcoidosis.
The integrin a sub(E)b sub(7) is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common single nucleotide polymorphisms spanning ITGAE, the gene encoding the a sub(E) (CD103) unit, were genotyped in 556 sarcoidosis patients and 465 controls. The -1088 A/G polymorphism was associated with sarcoidosis (P=0.004). An increased risk of disease was found for homozygous carriers of the A allele vs. carriers of the G allele (P=0.001, odds ratio=1.63 [1.22-2.17]). Analysis of lymphocytes from bronchoalveolar lavage and in vitro functional tests showed higher percentages of CD103+CD4+ T cells for the sarcoidosis risk genotype. Radiographic staging at disease outcome revealed prevalence of -1088 AA genotype in patients with fibrosis (P=0.01). A higher proportion of CD103+CD4+ T cells and ITGAE -1088 AA genotype might be associated with fibrosis formation in pulmonary sarcoidosis.
Abstract The integrin αE β7 is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common single nucleotide polymorphisms spanning ITGAE , the gene encoding the αE (CD103) unit, were genotyped in 556 sarcoidosis patients and 465 controls. The − 1088 A/G polymorphism was associated with sarcoidosis ( P = 0.004). An increased risk of disease was found for homozygous carriers of the A allele vs. carriers of the G allele ( P = 0.001, odds ratio = 1.63 [1.22–2.17]). Analysis of lymphocytes from bronchoalveolar lavage and in vitro functional tests showed higher percentages of CD103+CD4+ T cells for the sarcoidosis risk genotype. Radiographic staging at disease outcome revealed prevalence of − 1088 AA genotype in patients with fibrosis ( P = 0.01). A higher proportion of CD103+CD4+ T cells and ITGAE − 1088 AA genotype might be associated with fibrosis formation in pulmonary sarcoidosis.
Author Claessen, A.M.E
Heron, M
Van den Bosch, J.M.M
Grutters, J.C
Ruven, H.J.T
Van Moorsel, C.H.M
Kazemier, K.M
Author_xml – sequence: 1
  fullname: Heron, M
– sequence: 2
  fullname: Grutters, J.C
– sequence: 3
  fullname: Van Moorsel, C.H.M
– sequence: 4
  fullname: Ruven, H.J.T
– sequence: 5
  fullname: Kazemier, K.M
– sequence: 6
  fullname: Claessen, A.M.E
– sequence: 7
  fullname: Van den Bosch, J.M.M
BackLink https://www.ncbi.nlm.nih.gov/pubmed/19604725$$D View this record in MEDLINE/PubMed
BookMark eNqFkc1qGzEUhUVJaH7aF-iiaNVVPL2SRhoPlEJwnR8IZNF0VxCydNXIGUuuZIf67aPBhkIXKQh0Qd-5iO-ckaOYIhLygUHDgKnPy8YOYdVwgL4B1QB0b8gpk5xNOhDy6DArxdQJOStlCQCSc_WWnLBeQdtxeUp-zr1Hu6HJ02eTg9mEFGmI9Pbh-nJO65xDeRpfi8k2BZdKKBd09o2BoPhnnbGUmrigJjpqH7FsaDYupF_ZrB9378ixN0PB94f7nPy4mj_MbiZ399e3s8u7iW1b2Exk5ztQrlMeWy-55YIvpHAS6jHTFlvBDC4YgO8UYmusFzjlxjGvhGFmIc7Jp_3edU6_t_UTehWKxWEwEdO2aNUpCaoX_wU540zCFCrI96DNqZSMXq9zWJm80wz0KF8v9Shfj_I1KF3l19DHw_btYoXub-RguwJf9gBWGc8Bsy42YLToQq4laJfC6_u__hOvSAzWDE-4w7JM2xyrZs104Rr097H-sX3oaxraXrwAE_Wq8w
CitedBy_id crossref_primary_10_4049_jimmunol_2100220
crossref_primary_10_1371_journal_pone_0030442
crossref_primary_10_1038_srep24974
crossref_primary_10_1016_j_rmed_2016_08_003
crossref_primary_10_1007_s12016_015_8477_8
crossref_primary_10_1007_s00251_012_0604_6
crossref_primary_10_1111_j_1365_2796_2011_02414_x
crossref_primary_10_1016_j_rmed_2012_03_020
Cites_doi 10.1002/eji.1830250333
10.1002/eji.1830170910
10.1016/j.clim.2007.11.005
10.1136/thx.54.4.339
10.4049/jimmunol.144.7.2541
10.1038/ng.71
10.4049/jimmunol.178.9.5859
10.1164/ajrccm.163.1.9906071
10.1136/mp.52.4.203
10.1126/science.282.5397.2261
10.1016/S1359-6101(97)89237-4
10.1046/j.1365-2567.2001.01232.x
10.1002/jlb.48.4.367
10.1038/sj.hdy.6800717
10.1086/383251
10.1111/j.1365-3083.1995.tb03607.x
10.1126/science.272.5258.60
10.4049/jimmunol.162.11.6641
10.1093/intimm/14.4.339
10.1378/chest.102.3.882
10.1086/379378
10.1016/S0955-0674(00)00132-0
10.1093/bioinformatics/bth457
10.1056/NEJMoa0707865
10.1046/j.1365-2249.1999.00894.x
10.1164/rccm.200509-1518OC
10.1034/j.1399-3003.1999.14d02.x
10.1038/ng1669
10.1046/j.1365-2796.1998.00378.x
10.1182/blood-2008-01-134833
10.1002/cyto.b.10021
10.1038/nm1332
10.1056/NEJM198401263100406
10.1126/science.282.5397.2258
10.1016/j.jneuroim.2007.07.006
10.1038/nrg777
10.1378/chest.129.6.1584
10.1165/ajrcmb.10.3.7509610
10.1378/chest.08-0443
10.4049/jimmunol.165.11.6583
10.1073/pnas.192162899
10.1038/372190a0
10.1016/j.jneuroim.2007.06.015
10.1056/NEJMra071714
ContentType Journal Article
Copyright Elsevier Inc.
2009 Elsevier Inc.
Copyright_xml – notice: Elsevier Inc.
– notice: 2009 Elsevier Inc.
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7T5
H94
7X8
DOI 10.1016/j.clim.2009.06.007
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
Immunology Abstracts
AIDS and Cancer Research Abstracts
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
AIDS and Cancer Research Abstracts
Immunology Abstracts
MEDLINE - Academic
DatabaseTitleList
MEDLINE
MEDLINE - Academic
AIDS and Cancer Research Abstracts
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1521-7035
EndPage 125
ExternalDocumentID 10_1016_j_clim_2009_06_007
19604725
S1521661609007049
1_s2_0_S1521661609007049
Genre Journal Article
GroupedDBID ---
--K
--M
.1-
.55
.FO
.GJ
.~1
0R~
0SF
1B1
1P~
1RT
1~.
1~5
29B
4.4
457
4G.
53G
5GY
5RE
5VS
6J9
7-5
71M
8P~
AAAJQ
AACTN
AAEDT
AAEDW
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAQXK
AARKO
AAXKI
AAXUO
ABBQC
ABFNM
ABFRF
ABJNI
ABMAC
ABMZM
ABPPZ
ABXDB
ACDAQ
ACGFO
ACGFS
ACRLP
ADBBV
ADEZE
ADFGL
ADMUD
ADVLN
AEBSH
AEFWE
AEKER
AENEX
AEVXI
AFCTW
AFFNX
AFJKZ
AFKWA
AFRHN
AFTJW
AFXIZ
AGEKW
AGHFR
AGUBO
AGYEJ
AIEXJ
AIKHN
AITUG
AJOXV
AJRQY
AJUYK
AKRWK
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ANZVX
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLXMC
BNPGV
CAG
CJTIS
COF
CS3
DM4
DU5
EBS
EFBJH
EJD
EO8
EO9
EP2
EP3
F5P
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-Q
GBLVA
HVGLF
HX~
HZ~
IH2
IHE
J1W
K-O
KOM
L7B
LG5
LUGTX
M41
MO0
N9A
O-L
O9-
O9~
OAUVE
OK0
OZT
P-8
P-9
P2P
PC.
Q38
R2-
RIG
ROL
RPZ
SDF
SDG
SDP
SES
SEW
SPCBC
SSH
SSI
SSZ
T5K
X7M
XPP
Y6R
Z5R
ZGI
ZMT
~G-
AAIAV
ABLVK
ABYKQ
AHPSJ
AJBFU
EFLBG
LCYCR
ZA5
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7T5
H94
7X8
ID FETCH-LOGICAL-c440t-57f706d76fe4f52c232b53d50d50a84e431aeb100f76ee4acf3e82ad1f63a1ab3
IEDL.DBID AIKHN
ISSN 1521-6616
IngestDate Thu Aug 15 22:43:52 EDT 2024
Sat Aug 17 02:29:13 EDT 2024
Thu Sep 26 15:48:25 EDT 2024
Sat Sep 28 07:57:05 EDT 2024
Fri Feb 23 02:15:15 EST 2024
Tue Oct 15 22:56:29 EDT 2024
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords Single nuclear polymorphism
ITGAE
Sarcoidosis
CD103
Epithelium
Fibrosis
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c440t-57f706d76fe4f52c232b53d50d50a84e431aeb100f76ee4acf3e82ad1f63a1ab3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
PMID 19604725
PQID 21215080
PQPubID 23462
PageCount 9
ParticipantIDs proquest_miscellaneous_67650693
proquest_miscellaneous_21215080
crossref_primary_10_1016_j_clim_2009_06_007
pubmed_primary_19604725
elsevier_sciencedirect_doi_10_1016_j_clim_2009_06_007
elsevier_clinicalkeyesjournals_1_s2_0_S1521661609007049
PublicationCentury 2000
PublicationDate 2009-10-01
PublicationDateYYYYMMDD 2009-10-01
PublicationDate_xml – month: 10
  year: 2009
  text: 2009-10-01
  day: 01
PublicationDecade 2000
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Clinical immunology (Orlando, Fla.)
PublicationTitleAlternate Clin Immunol
PublicationYear 2009
Publisher Elsevier Inc
Publisher_xml – name: Elsevier Inc
References Robinson, Green, Carter, Coadwell, Kilshaw (bib37) 2001; 103
S. Schlickum, H. Sennefelder, M. Friedrich, G. Harms, M.J. Lohse, P. Kilshaw, M.P. Schon, Integrin {alpha}E(CD103){beta}7 influences cellular shape and motility in a ligand-dependent fashion. Blood2008).
Kilshaw (bib15) 1999; 52
Wahlstrom, Katchar, Wigzell, Olerup, Eklund, Grunewald (bib5) 2001; 163
Kauffmann (bib24) 1994; 5
Costabel, Hunninghake (bib22) 1999; 14
de Bakker, Yelensky, Pe'er, Gabriel, Daly, Altshuler (bib25) 2005; 37
Fichtner-Feigl, Fuss, Young, Watanabe, Geissler, Schlitt, Kitani, Strober (bib44) 2007; 178
Hunninghake, Costabel, Ando, Baughman, Cordier, du, Eklund, Kitaichi, Lynch, Rizzato, Rose, Selroos, Semenzato, Sharma (bib23) 1999; 16
Heron, Slieker, Zanen, van Lochem, Hooijkaas, van den Bosch, van Velzen-Blad (bib35) 2008; 126
Grunig, Warnock, Wakil, Venkayya, Brombacher, Rennick, Sheppard, Mohrs, Donaldson, Locksley, Corry (bib45) 1998; 282
Wills-Karp, Luyimbazi, Xu, Schofield, Neben, Karp, Donaldson (bib46) 1998; 282
Brew, West, Burthem, Christmas (bib38) 1995; 41
Erle, Brown, Christian, Aris (bib12) 1994; 10
Lehmann, Huehn, de la, Maszyna, Kretschmer, Krenn, Brunner, Scheffold, Hamann (bib42) 2002; 99
Cepek, Shaw, Parker, Russell, Morrow, Rimm, Brenner (bib11) 1994; 372
Schon, Schon, Warren, Donohue, Parker (bib21) 2000; 165
Nath, Han, Kim-Howard, Kelly, Viswanathan, Gilkeson, Chen, Zhu, McEver, Kimberly, arcon-Riquelme, Vyse, Li, Wakeland, Merrill, James, Kaufman, Guthridge, Harley (bib19) 2008; 40
Nyholt (bib27) 2004; 74
Wahlstrom, Berlin, Skold, Wigzell, Eklund, Grunewald (bib34) 1999; 54
Crystal, Bitterman, Rennard, Hance, Keogh (bib2) 1984; 310
Prasse, Pechkovsky, Toews, Jungraithmayr, Kollert, Goldmann, Vollmer, Muller-Quernheim, Zissel (bib4) 2006; 173
Ardlie, Kruglyak, Seielstad (bib29) 2002; 3
Schieferdecker, Ullrich, Weiss-Breckwoldt, Schwarting, Stein, Riecken, Zeitz (bib10) 1990; 144
Iannuzzi, Rybicki, Teirstein (bib1) 2007; 357
Kruit, Grutters, Ruven, van Moorsel, Weiskirchen, Mengsteab, van den Bosch (bib3) 2006; 129
Taub (bib6) 1996; 7
Fichtner-Feigl, Strober, Kawakami, Puri, Kitani (bib43) 2006; 12
Singer (bib8) 1990; 48
O'Doherty, Roos, Antiguedad, Aransay, Hillert, Vandenbroeck (bib17) 2007; 189
Andreoli, Cittadella, Valentino, Condino, La, Liguori, Manna, Spadafora, Nistico, Pirritano, Clodomiro, Quattrone (bib16) 2007; 189
Li, Ji (bib26) 2005; 95
Cerf-Bensussan, Jarry, Brousse, Lisowska-Grospierre, Guy-Grand, Griscelli, monoclonal antibody (bib9) 1987; 17
Suzuki, Nakao, Kanamaru, Okumura, Ogawa, Ra (bib39) 2002; 14
Barrett, Fry, Maller, Daly (bib28) 2005; 21
Lohmeyer, Friedrich, Grimminger, Maus, Tenter, Morr, Velcovsky, Seeger, Rosseau (bib36) 1999; 116
Stephens, Donnelly (bib30) 2003; 73
Striz, Wang, Kalaycioglu, Costabel (bib33) 1992; 102
Hom, Graham, Modrek, Taylor, Ortmann, Garnier, Lee, Chung, Ferreira, Pant, Ballinger, Kosoy, Demirci, Kamboh, Kao, Tian, Gunnarsson, Bengtsson, Rantapaa-Dahlqvist, Petri, Manzi, Seldin, Ronnblom, Syvanen, Criswell, Gregersen, Behrens (bib18) 2008; 358
Heron, Grutters, van Velzen-Blad, Veltkamp, Claessen, van den Bosch (bib32) 2008; 134
Agace, Higgins, Sadasivan, Brenner, Parker (bib40) 2000; 12
Butcher, Picker (bib7) 1996; 272
Karecla, Bowden, Green, Kilshaw (bib13) 1995; 25
Schon, Arya, Murphy, Adams, Strauch, Agace, Marsal, Donohue, Her, Beier, Olson, Lefrancois, Brenner, Grusby, Parker (bib20) 1999; 162
Berlin, Lundahl, Skold, Grunewald, Eklund (bib31) 1998; 244
Braun, Foerster, Grahmann, Haefner, Workalemahu, Kroegel (bib41) 2003; 54
Taub (10.1016/j.clim.2009.06.007_bib6) 1996; 7
Heron (10.1016/j.clim.2009.06.007_bib32) 2008; 134
Andreoli (10.1016/j.clim.2009.06.007_bib16) 2007; 189
Erle (10.1016/j.clim.2009.06.007_bib12) 1994; 10
Fichtner-Feigl (10.1016/j.clim.2009.06.007_bib44) 2007; 178
Agace (10.1016/j.clim.2009.06.007_bib40) 2000; 12
Stephens (10.1016/j.clim.2009.06.007_bib30) 2003; 73
Karecla (10.1016/j.clim.2009.06.007_bib13) 1995; 25
Prasse (10.1016/j.clim.2009.06.007_bib4) 2006; 173
Schieferdecker (10.1016/j.clim.2009.06.007_bib10) 1990; 144
Brew (10.1016/j.clim.2009.06.007_bib38) 1995; 41
Schon (10.1016/j.clim.2009.06.007_bib21) 2000; 165
Iannuzzi (10.1016/j.clim.2009.06.007_bib1) 2007; 357
Kilshaw (10.1016/j.clim.2009.06.007_bib15) 1999; 52
de Bakker (10.1016/j.clim.2009.06.007_bib25) 2005; 37
Hunninghake (10.1016/j.clim.2009.06.007_bib23) 1999; 16
Suzuki (10.1016/j.clim.2009.06.007_bib39) 2002; 14
Hom (10.1016/j.clim.2009.06.007_bib18) 2008; 358
Heron (10.1016/j.clim.2009.06.007_bib35) 2008; 126
Cerf-Bensussan (10.1016/j.clim.2009.06.007_bib9) 1987; 17
Barrett (10.1016/j.clim.2009.06.007_bib28) 2005; 21
Nath (10.1016/j.clim.2009.06.007_bib19) 2008; 40
Ardlie (10.1016/j.clim.2009.06.007_bib29) 2002; 3
Schon (10.1016/j.clim.2009.06.007_bib20) 1999; 162
Wahlstrom (10.1016/j.clim.2009.06.007_bib34) 1999; 54
Wills-Karp (10.1016/j.clim.2009.06.007_bib46) 1998; 282
Cepek (10.1016/j.clim.2009.06.007_bib11) 1994; 372
Crystal (10.1016/j.clim.2009.06.007_bib2) 1984; 310
Kruit (10.1016/j.clim.2009.06.007_bib3) 2006; 129
10.1016/j.clim.2009.06.007_bib14
Striz (10.1016/j.clim.2009.06.007_bib33) 1992; 102
Wahlstrom (10.1016/j.clim.2009.06.007_bib5) 2001; 163
Nyholt (10.1016/j.clim.2009.06.007_bib27) 2004; 74
Lohmeyer (10.1016/j.clim.2009.06.007_bib36) 1999; 116
Robinson (10.1016/j.clim.2009.06.007_bib37) 2001; 103
Lehmann (10.1016/j.clim.2009.06.007_bib42) 2002; 99
Berlin (10.1016/j.clim.2009.06.007_bib31) 1998; 244
Kauffmann (10.1016/j.clim.2009.06.007_bib24) 1994; 5
Butcher (10.1016/j.clim.2009.06.007_bib7) 1996; 272
Costabel (10.1016/j.clim.2009.06.007_bib22) 1999; 14
Singer (10.1016/j.clim.2009.06.007_bib8) 1990; 48
Fichtner-Feigl (10.1016/j.clim.2009.06.007_bib43) 2006; 12
Braun (10.1016/j.clim.2009.06.007_bib41) 2003; 54
O'Doherty (10.1016/j.clim.2009.06.007_bib17) 2007; 189
Grunig (10.1016/j.clim.2009.06.007_bib45) 1998; 282
Li (10.1016/j.clim.2009.06.007_bib26) 2005; 95
References_xml – volume: 37
  start-page: 1217
  year: 2005
  end-page: 1223
  ident: bib25
  article-title: Efficiency and power in genetic association studies
  publication-title: Nat. Genet.
  contributor:
    fullname: Altshuler
– volume: 372
  start-page: 190
  year: 1994
  end-page: 193
  ident: bib11
  article-title: Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin
  publication-title: Nature
  contributor:
    fullname: Brenner
– volume: 3
  start-page: 299
  year: 2002
  end-page: 309
  ident: bib29
  article-title: Patterns of linkage disequilibrium in the human genome
  publication-title: Nat. Rev., Genet.
  contributor:
    fullname: Seielstad
– volume: 163
  start-page: 115
  year: 2001
  end-page: 121
  ident: bib5
  article-title: Analysis of intracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis
  publication-title: Am. J. Respir. Crit. Care Med.
  contributor:
    fullname: Grunewald
– volume: 48
  start-page: 367
  year: 1990
  end-page: 374
  ident: bib8
  article-title: Interactions between epithelial cells and T lymphocytes: role of adhesion molecules
  publication-title: J. Leukoc. Biol.
  contributor:
    fullname: Singer
– volume: 189
  start-page: 125
  year: 2007
  end-page: 128
  ident: bib16
  article-title: The role of VLA4 polymorphisms in multiple sclerosis: an association study
  publication-title: J. Neuroimmunol.
  contributor:
    fullname: Quattrone
– volume: 12
  start-page: 99
  year: 2006
  end-page: 106
  ident: bib43
  article-title: IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis
  publication-title: Nat. Med.
  contributor:
    fullname: Kitani
– volume: 7
  start-page: 355
  year: 1996
  end-page: 376
  ident: bib6
  article-title: Chemokine–leukocyte interactions. The voodoo that they do so well
  publication-title: Cytokine Growth Factor Rev.
  contributor:
    fullname: Taub
– volume: 40
  start-page: 152
  year: 2008
  end-page: 154
  ident: bib19
  article-title: A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus
  publication-title: Nat. Genet.
  contributor:
    fullname: Harley
– volume: 103
  start-page: 146
  year: 2001
  end-page: 154
  ident: bib37
  article-title: Studies on transcriptional regulation of the mucosal T-cell integrin alphaEbeta7 (CD103)
  publication-title: Immunology
  contributor:
    fullname: Kilshaw
– volume: 54
  start-page: 339
  year: 1999
  end-page: 346
  ident: bib34
  article-title: Phenotypic analysis of lymphocytes and monocytes/macrophages in peripheral blood and bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
  publication-title: Thorax
  contributor:
    fullname: Grunewald
– volume: 310
  start-page: 235
  year: 1984
  end-page: 244
  ident: bib2
  article-title: Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract
  publication-title: N. Engl. J. Med.
  contributor:
    fullname: Keogh
– volume: 99
  start-page: 13031
  year: 2002
  end-page: 13036
  ident: bib42
  article-title: Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Hamann
– volume: 14
  start-page: 735
  year: 1999
  end-page: 737
  ident: bib22
  article-title: ATS/ERS/WASOG statement on sarcoidosis. Sarcoidosis Statement Committee. American Thoracic Society. European Respiratory Society. World Association for Sarcoidosis and Other Granulomatous Disorders
  publication-title: Eur. Respir. J.
  contributor:
    fullname: Hunninghake
– volume: 14
  start-page: 339
  year: 2002
  end-page: 345
  ident: bib39
  article-title: Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta
  publication-title: Int. Immunol.
  contributor:
    fullname: Ra
– volume: 95
  start-page: 221
  year: 2005
  end-page: 227
  ident: bib26
  article-title: Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
  publication-title: Heredity
  contributor:
    fullname: Ji
– volume: 54
  start-page: 19
  year: 2003
  end-page: 27
  ident: bib41
  article-title: Phenotypic and molecular characterization of CD103+ CD4+ T cells in bronchoalveolar lavage from patients with interstitial lung diseases
  publication-title: Cytometry B Clin. Cytom.
  contributor:
    fullname: Kroegel
– volume: 73
  start-page: 1162
  year: 2003
  end-page: 1169
  ident: bib30
  article-title: A comparison of Bayesian methods for haplotype reconstruction from population genotype data
  publication-title: Am. J. Hum. Genet.
  contributor:
    fullname: Donnelly
– volume: 41
  start-page: 553
  year: 1995
  end-page: 562
  ident: bib38
  article-title: Expression of the human mucosal lymphocyte antigen, HML-1, by T cells activated with mitogen or specific antigen in vitro
  publication-title: Scand. J. Immunol.
  contributor:
    fullname: Christmas
– volume: 358
  start-page: 900
  year: 2008
  end-page: 909
  ident: bib18
  article-title: Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
  publication-title: N. Engl. J Med
  contributor:
    fullname: Behrens
– volume: 74
  start-page: 765
  year: 2004
  end-page: 769
  ident: bib27
  article-title: A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
  publication-title: Am. J. Hum. Genet.
  contributor:
    fullname: Nyholt
– volume: 129
  start-page: 1584
  year: 2006
  end-page: 1591
  ident: bib3
  article-title: Transforming growth factor-beta gene polymorphisms in sarcoidosis patients with and without fibrosis
  publication-title: Chest
  contributor:
    fullname: van den Bosch
– volume: 17
  start-page: 1279
  year: 1987
  end-page: 1285
  ident: bib9
  article-title: (HML-1) defining a novel membrane molecule present on human intestinal lymphocytes
  publication-title: Eur. J. Immunol.
  contributor:
    fullname: monoclonal antibody
– volume: 162
  start-page: 6641
  year: 1999
  end-page: 6649
  ident: bib20
  article-title: Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice
  publication-title: J. Immunol.
  contributor:
    fullname: Parker
– volume: 244
  start-page: 333
  year: 1998
  end-page: 340
  ident: bib31
  article-title: The lymphocytic alveolitis in sarcoidosis is associated with increased amounts of soluble and cell-bound adhesion molecules in bronchoalveolar lavage fluid and serum
  publication-title: J. Intern. Med
  contributor:
    fullname: Eklund
– volume: 102
  start-page: 882
  year: 1992
  end-page: 886
  ident: bib33
  article-title: Expression of alveolar macrophage adhesion molecules in pulmonary sarcoidosis
  publication-title: Chest
  contributor:
    fullname: Costabel
– volume: 282
  start-page: 2261
  year: 1998
  end-page: 2263
  ident: bib45
  article-title: Requirement for IL-13 independently of IL-4 in experimental asthma
  publication-title: Science
  contributor:
    fullname: Corry
– volume: 144
  start-page: 2541
  year: 1990
  end-page: 2549
  ident: bib10
  article-title: The HML-1 antigen of intestinal lymphocytes is an activation antigen
  publication-title: J. Immunol.
  contributor:
    fullname: Zeitz
– volume: 165
  start-page: 6583
  year: 2000
  end-page: 6589
  ident: bib21
  article-title: Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient mice
  publication-title: J. Immunol.
  contributor:
    fullname: Parker
– volume: 12
  start-page: 563
  year: 2000
  end-page: 568
  ident: bib40
  article-title: T-lymphocyte–epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines
  publication-title: Curr. Opin. Cell Biol.
  contributor:
    fullname: Parker
– volume: 272
  start-page: 60
  year: 1996
  end-page: 66
  ident: bib7
  article-title: Lymphocyte homing and homeostasis
  publication-title: Science
  contributor:
    fullname: Picker
– volume: 189
  start-page: 151
  year: 2007
  end-page: 157
  ident: bib17
  article-title: ITGA4 polymorphisms and susceptibility to multiple sclerosis
  publication-title: J. Neuroimmunol.
  contributor:
    fullname: Vandenbroeck
– volume: 5
  start-page: 66
  year: 1994
  end-page: 68
  ident: bib24
  article-title: Standaardisatie van het protocol voor bronchoalveolaire lavage in Nederland
  publication-title: Pulmoscript
  contributor:
    fullname: Kauffmann
– volume: 178
  start-page: 5859
  year: 2007
  end-page: 5870
  ident: bib44
  article-title: Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis
  publication-title: J. Immunol.
  contributor:
    fullname: Strober
– volume: 10
  start-page: 237
  year: 1994
  end-page: 244
  ident: bib12
  article-title: Lung epithelial lining fluid T cell subsets defined by distinct patterns of beta 7 and beta 1 integrin expression
  publication-title: Am. J. Respir. Cell Mol. Biol.
  contributor:
    fullname: Aris
– volume: 126
  start-page: 338
  year: 2008
  end-page: 344
  ident: bib35
  article-title: Evaluation of CD103 as a cellular marker for the diagnosis of pulmonary sarcoidosis
  publication-title: Clin. Immunol.
  contributor:
    fullname: van Velzen-Blad
– volume: 282
  start-page: 2258
  year: 1998
  end-page: 2261
  ident: bib46
  article-title: Interleukin-13: central mediator of allergic asthma
  publication-title: Science
  contributor:
    fullname: Donaldson
– volume: 173
  start-page: 781
  year: 2006
  end-page: 792
  ident: bib4
  article-title: A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18
  publication-title: Am. J. Respir. Crit. Care Med.
  contributor:
    fullname: Zissel
– volume: 21
  start-page: 263
  year: 2005
  end-page: 265
  ident: bib28
  article-title: Haploview: analysis and visualization of LD and haplotype maps
  publication-title: Bioinformatics
  contributor:
    fullname: Daly
– volume: 134
  start-page: 1001
  year: 2008
  end-page: 1008
  ident: bib32
  article-title: Increased expression of CD16, CD69, and very late antigen-1 on blood monocytes in active sarcoidosis
  publication-title: Chest
  contributor:
    fullname: van den Bosch
– volume: 25
  start-page: 852
  year: 1995
  end-page: 856
  ident: bib13
  article-title: Recognition of E-cadherin on epithelial cells by the mucosal T cell integrin alpha M290 beta 7 (alpha E beta 7)
  publication-title: Eur. J Immunol.
  contributor:
    fullname: Kilshaw
– volume: 116
  start-page: 340
  year: 1999
  end-page: 346
  ident: bib36
  article-title: Expression of mucosa-related integrin alphaEbeta7 on alveolar T cells in interstitial lung diseases
  publication-title: Clin. Exp. Immunol.
  contributor:
    fullname: Rosseau
– volume: 357
  start-page: 2153
  year: 2007
  end-page: 2165
  ident: bib1
  article-title: Sarcoidosis
  publication-title: N. Engl. J Med
  contributor:
    fullname: Teirstein
– volume: 52
  start-page: 203
  year: 1999
  end-page: 207
  ident: bib15
  article-title: Alpha E beta 7
  publication-title: Mol. Pathol.
  contributor:
    fullname: Kilshaw
– volume: 16
  start-page: 149
  year: 1999
  end-page: 173
  ident: bib23
  article-title: ATS/ERS/WASOG statement on sarcoidosis. American Thoracic Society/European Respiratory Society/World Association of Sarcoidosis and other Granulomatous Disorders
  publication-title: Sarcoidosis Vasc. Diffuse Lung Dis.
  contributor:
    fullname: Sharma
– volume: 25
  start-page: 852
  year: 1995
  ident: 10.1016/j.clim.2009.06.007_bib13
  article-title: Recognition of E-cadherin on epithelial cells by the mucosal T cell integrin alpha M290 beta 7 (alpha E beta 7)
  publication-title: Eur. J Immunol.
  doi: 10.1002/eji.1830250333
  contributor:
    fullname: Karecla
– volume: 17
  start-page: 1279
  year: 1987
  ident: 10.1016/j.clim.2009.06.007_bib9
  article-title: (HML-1) defining a novel membrane molecule present on human intestinal lymphocytes
  publication-title: Eur. J. Immunol.
  doi: 10.1002/eji.1830170910
  contributor:
    fullname: Cerf-Bensussan
– volume: 126
  start-page: 338
  year: 2008
  ident: 10.1016/j.clim.2009.06.007_bib35
  article-title: Evaluation of CD103 as a cellular marker for the diagnosis of pulmonary sarcoidosis
  publication-title: Clin. Immunol.
  doi: 10.1016/j.clim.2007.11.005
  contributor:
    fullname: Heron
– volume: 54
  start-page: 339
  year: 1999
  ident: 10.1016/j.clim.2009.06.007_bib34
  article-title: Phenotypic analysis of lymphocytes and monocytes/macrophages in peripheral blood and bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
  publication-title: Thorax
  doi: 10.1136/thx.54.4.339
  contributor:
    fullname: Wahlstrom
– volume: 144
  start-page: 2541
  year: 1990
  ident: 10.1016/j.clim.2009.06.007_bib10
  article-title: The HML-1 antigen of intestinal lymphocytes is an activation antigen
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.144.7.2541
  contributor:
    fullname: Schieferdecker
– volume: 40
  start-page: 152
  year: 2008
  ident: 10.1016/j.clim.2009.06.007_bib19
  article-title: A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus
  publication-title: Nat. Genet.
  doi: 10.1038/ng.71
  contributor:
    fullname: Nath
– volume: 178
  start-page: 5859
  year: 2007
  ident: 10.1016/j.clim.2009.06.007_bib44
  article-title: Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.178.9.5859
  contributor:
    fullname: Fichtner-Feigl
– volume: 163
  start-page: 115
  year: 2001
  ident: 10.1016/j.clim.2009.06.007_bib5
  article-title: Analysis of intracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis
  publication-title: Am. J. Respir. Crit. Care Med.
  doi: 10.1164/ajrccm.163.1.9906071
  contributor:
    fullname: Wahlstrom
– volume: 52
  start-page: 203
  year: 1999
  ident: 10.1016/j.clim.2009.06.007_bib15
  article-title: Alpha E beta 7
  publication-title: Mol. Pathol.
  doi: 10.1136/mp.52.4.203
  contributor:
    fullname: Kilshaw
– volume: 282
  start-page: 2261
  year: 1998
  ident: 10.1016/j.clim.2009.06.007_bib45
  article-title: Requirement for IL-13 independently of IL-4 in experimental asthma
  publication-title: Science
  doi: 10.1126/science.282.5397.2261
  contributor:
    fullname: Grunig
– volume: 7
  start-page: 355
  year: 1996
  ident: 10.1016/j.clim.2009.06.007_bib6
  article-title: Chemokine–leukocyte interactions. The voodoo that they do so well
  publication-title: Cytokine Growth Factor Rev.
  doi: 10.1016/S1359-6101(97)89237-4
  contributor:
    fullname: Taub
– volume: 103
  start-page: 146
  year: 2001
  ident: 10.1016/j.clim.2009.06.007_bib37
  article-title: Studies on transcriptional regulation of the mucosal T-cell integrin alphaEbeta7 (CD103)
  publication-title: Immunology
  doi: 10.1046/j.1365-2567.2001.01232.x
  contributor:
    fullname: Robinson
– volume: 48
  start-page: 367
  year: 1990
  ident: 10.1016/j.clim.2009.06.007_bib8
  article-title: Interactions between epithelial cells and T lymphocytes: role of adhesion molecules
  publication-title: J. Leukoc. Biol.
  doi: 10.1002/jlb.48.4.367
  contributor:
    fullname: Singer
– volume: 95
  start-page: 221
  year: 2005
  ident: 10.1016/j.clim.2009.06.007_bib26
  article-title: Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
  publication-title: Heredity
  doi: 10.1038/sj.hdy.6800717
  contributor:
    fullname: Li
– volume: 16
  start-page: 149
  year: 1999
  ident: 10.1016/j.clim.2009.06.007_bib23
  article-title: ATS/ERS/WASOG statement on sarcoidosis. American Thoracic Society/European Respiratory Society/World Association of Sarcoidosis and other Granulomatous Disorders
  publication-title: Sarcoidosis Vasc. Diffuse Lung Dis.
  contributor:
    fullname: Hunninghake
– volume: 74
  start-page: 765
  year: 2004
  ident: 10.1016/j.clim.2009.06.007_bib27
  article-title: A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
  publication-title: Am. J. Hum. Genet.
  doi: 10.1086/383251
  contributor:
    fullname: Nyholt
– volume: 41
  start-page: 553
  year: 1995
  ident: 10.1016/j.clim.2009.06.007_bib38
  article-title: Expression of the human mucosal lymphocyte antigen, HML-1, by T cells activated with mitogen or specific antigen in vitro
  publication-title: Scand. J. Immunol.
  doi: 10.1111/j.1365-3083.1995.tb03607.x
  contributor:
    fullname: Brew
– volume: 272
  start-page: 60
  year: 1996
  ident: 10.1016/j.clim.2009.06.007_bib7
  article-title: Lymphocyte homing and homeostasis
  publication-title: Science
  doi: 10.1126/science.272.5258.60
  contributor:
    fullname: Butcher
– volume: 162
  start-page: 6641
  year: 1999
  ident: 10.1016/j.clim.2009.06.007_bib20
  article-title: Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.162.11.6641
  contributor:
    fullname: Schon
– volume: 14
  start-page: 339
  year: 2002
  ident: 10.1016/j.clim.2009.06.007_bib39
  article-title: Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta
  publication-title: Int. Immunol.
  doi: 10.1093/intimm/14.4.339
  contributor:
    fullname: Suzuki
– volume: 102
  start-page: 882
  year: 1992
  ident: 10.1016/j.clim.2009.06.007_bib33
  article-title: Expression of alveolar macrophage adhesion molecules in pulmonary sarcoidosis
  publication-title: Chest
  doi: 10.1378/chest.102.3.882
  contributor:
    fullname: Striz
– volume: 73
  start-page: 1162
  year: 2003
  ident: 10.1016/j.clim.2009.06.007_bib30
  article-title: A comparison of Bayesian methods for haplotype reconstruction from population genotype data
  publication-title: Am. J. Hum. Genet.
  doi: 10.1086/379378
  contributor:
    fullname: Stephens
– volume: 12
  start-page: 563
  year: 2000
  ident: 10.1016/j.clim.2009.06.007_bib40
  article-title: T-lymphocyte–epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines
  publication-title: Curr. Opin. Cell Biol.
  doi: 10.1016/S0955-0674(00)00132-0
  contributor:
    fullname: Agace
– volume: 21
  start-page: 263
  year: 2005
  ident: 10.1016/j.clim.2009.06.007_bib28
  article-title: Haploview: analysis and visualization of LD and haplotype maps
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/bth457
  contributor:
    fullname: Barrett
– volume: 358
  start-page: 900
  year: 2008
  ident: 10.1016/j.clim.2009.06.007_bib18
  article-title: Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
  publication-title: N. Engl. J Med
  doi: 10.1056/NEJMoa0707865
  contributor:
    fullname: Hom
– volume: 116
  start-page: 340
  year: 1999
  ident: 10.1016/j.clim.2009.06.007_bib36
  article-title: Expression of mucosa-related integrin alphaEbeta7 on alveolar T cells in interstitial lung diseases
  publication-title: Clin. Exp. Immunol.
  doi: 10.1046/j.1365-2249.1999.00894.x
  contributor:
    fullname: Lohmeyer
– volume: 173
  start-page: 781
  year: 2006
  ident: 10.1016/j.clim.2009.06.007_bib4
  article-title: A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18
  publication-title: Am. J. Respir. Crit. Care Med.
  doi: 10.1164/rccm.200509-1518OC
  contributor:
    fullname: Prasse
– volume: 14
  start-page: 735
  year: 1999
  ident: 10.1016/j.clim.2009.06.007_bib22
  article-title: ATS/ERS/WASOG statement on sarcoidosis. Sarcoidosis Statement Committee. American Thoracic Society. European Respiratory Society. World Association for Sarcoidosis and Other Granulomatous Disorders
  publication-title: Eur. Respir. J.
  doi: 10.1034/j.1399-3003.1999.14d02.x
  contributor:
    fullname: Costabel
– volume: 37
  start-page: 1217
  year: 2005
  ident: 10.1016/j.clim.2009.06.007_bib25
  article-title: Efficiency and power in genetic association studies
  publication-title: Nat. Genet.
  doi: 10.1038/ng1669
  contributor:
    fullname: de Bakker
– volume: 244
  start-page: 333
  year: 1998
  ident: 10.1016/j.clim.2009.06.007_bib31
  article-title: The lymphocytic alveolitis in sarcoidosis is associated with increased amounts of soluble and cell-bound adhesion molecules in bronchoalveolar lavage fluid and serum
  publication-title: J. Intern. Med
  doi: 10.1046/j.1365-2796.1998.00378.x
  contributor:
    fullname: Berlin
– ident: 10.1016/j.clim.2009.06.007_bib14
  doi: 10.1182/blood-2008-01-134833
– volume: 54
  start-page: 19
  year: 2003
  ident: 10.1016/j.clim.2009.06.007_bib41
  article-title: Phenotypic and molecular characterization of CD103+ CD4+ T cells in bronchoalveolar lavage from patients with interstitial lung diseases
  publication-title: Cytometry B Clin. Cytom.
  doi: 10.1002/cyto.b.10021
  contributor:
    fullname: Braun
– volume: 12
  start-page: 99
  year: 2006
  ident: 10.1016/j.clim.2009.06.007_bib43
  article-title: IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis
  publication-title: Nat. Med.
  doi: 10.1038/nm1332
  contributor:
    fullname: Fichtner-Feigl
– volume: 310
  start-page: 235
  year: 1984
  ident: 10.1016/j.clim.2009.06.007_bib2
  article-title: Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM198401263100406
  contributor:
    fullname: Crystal
– volume: 282
  start-page: 2258
  year: 1998
  ident: 10.1016/j.clim.2009.06.007_bib46
  article-title: Interleukin-13: central mediator of allergic asthma
  publication-title: Science
  doi: 10.1126/science.282.5397.2258
  contributor:
    fullname: Wills-Karp
– volume: 189
  start-page: 151
  year: 2007
  ident: 10.1016/j.clim.2009.06.007_bib17
  article-title: ITGA4 polymorphisms and susceptibility to multiple sclerosis
  publication-title: J. Neuroimmunol.
  doi: 10.1016/j.jneuroim.2007.07.006
  contributor:
    fullname: O'Doherty
– volume: 3
  start-page: 299
  year: 2002
  ident: 10.1016/j.clim.2009.06.007_bib29
  article-title: Patterns of linkage disequilibrium in the human genome
  publication-title: Nat. Rev., Genet.
  doi: 10.1038/nrg777
  contributor:
    fullname: Ardlie
– volume: 129
  start-page: 1584
  year: 2006
  ident: 10.1016/j.clim.2009.06.007_bib3
  article-title: Transforming growth factor-beta gene polymorphisms in sarcoidosis patients with and without fibrosis
  publication-title: Chest
  doi: 10.1378/chest.129.6.1584
  contributor:
    fullname: Kruit
– volume: 10
  start-page: 237
  year: 1994
  ident: 10.1016/j.clim.2009.06.007_bib12
  article-title: Lung epithelial lining fluid T cell subsets defined by distinct patterns of beta 7 and beta 1 integrin expression
  publication-title: Am. J. Respir. Cell Mol. Biol.
  doi: 10.1165/ajrcmb.10.3.7509610
  contributor:
    fullname: Erle
– volume: 134
  start-page: 1001
  year: 2008
  ident: 10.1016/j.clim.2009.06.007_bib32
  article-title: Increased expression of CD16, CD69, and very late antigen-1 on blood monocytes in active sarcoidosis
  publication-title: Chest
  doi: 10.1378/chest.08-0443
  contributor:
    fullname: Heron
– volume: 165
  start-page: 6583
  year: 2000
  ident: 10.1016/j.clim.2009.06.007_bib21
  article-title: Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient mice
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.165.11.6583
  contributor:
    fullname: Schon
– volume: 99
  start-page: 13031
  year: 2002
  ident: 10.1016/j.clim.2009.06.007_bib42
  article-title: Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.192162899
  contributor:
    fullname: Lehmann
– volume: 372
  start-page: 190
  year: 1994
  ident: 10.1016/j.clim.2009.06.007_bib11
  article-title: Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin
  publication-title: Nature
  doi: 10.1038/372190a0
  contributor:
    fullname: Cepek
– volume: 189
  start-page: 125
  year: 2007
  ident: 10.1016/j.clim.2009.06.007_bib16
  article-title: The role of VLA4 polymorphisms in multiple sclerosis: an association study
  publication-title: J. Neuroimmunol.
  doi: 10.1016/j.jneuroim.2007.06.015
  contributor:
    fullname: Andreoli
– volume: 5
  start-page: 66
  year: 1994
  ident: 10.1016/j.clim.2009.06.007_bib24
  article-title: Standaardisatie van het protocol voor bronchoalveolaire lavage in Nederland
  publication-title: Pulmoscript
  contributor:
    fullname: Kauffmann
– volume: 357
  start-page: 2153
  year: 2007
  ident: 10.1016/j.clim.2009.06.007_bib1
  article-title: Sarcoidosis
  publication-title: N. Engl. J Med
  doi: 10.1056/NEJMra071714
  contributor:
    fullname: Iannuzzi
SSID ssj0005226
Score 2.0124347
Snippet Abstract The integrin αE β7 is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common single...
The integrin α Eβ 7 is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common single...
The integrin alpha(E)beta(7) is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common...
The integrin a sub(E)b sub(7) is believed to play a key role in retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. Five common...
SourceID proquest
crossref
pubmed
elsevier
SourceType Aggregation Database
Index Database
Publisher
StartPage 117
SubjectTerms Alleles
Allergy and Immunology
Antigens, CD - genetics
Antigens, CD - immunology
Bronchoalveolar Lavage Fluid - immunology
CD103
CD4-Positive T-Lymphocytes - immunology
CD4-Positive T-Lymphocytes - metabolism
CD8-Positive T-Lymphocytes - immunology
CD8-Positive T-Lymphocytes - metabolism
Epithelium
Exons - genetics
Exons - immunology
Female
Fibrosis
Gene Frequency - genetics
Gene Frequency - immunology
Genetic Predisposition to Disease
Genotype
Humans
Integrin alpha Chains - genetics
Integrin alpha Chains - immunology
Introns - genetics
Introns - immunology
ITGAE
Linkage Disequilibrium - genetics
Linkage Disequilibrium - immunology
Male
Polymorphism, Single Nucleotide
Promoter Regions, Genetic - genetics
Promoter Regions, Genetic - immunology
Radiography
Sarcoidosis
Sarcoidosis - diagnostic imaging
Sarcoidosis - genetics
Sarcoidosis - immunology
Single nuclear polymorphism
Title Effect of variation in ITGAE on risk of sarcoidosis, CD103 expression, and chest radiography
URI https://www.clinicalkey.es/playcontent/1-s2.0-S1521661609007049
https://dx.doi.org/10.1016/j.clim.2009.06.007
https://www.ncbi.nlm.nih.gov/pubmed/19604725
https://search.proquest.com/docview/21215080
https://search.proquest.com/docview/67650693
Volume 133
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB61WwlxQeW90BYfuNGwdvxaH1fbli2ovdBKPSBZTuxIqSCpmi3ixG9nnDg8hJYDUg5RYifO2J75opn5BuB1wbgojXaZL8tIqm145tAuZp65eW7mtDQqJiefnavVpXh_Ja-2YDnmwsSwyqT7B53ea-t0ZZakObup69nHaHnQuihqImeNMNuwg-ZIiAnsLE4_rM5_i_Toq67F9lnskHJnhjCv8nP9JdFWRreE3mSfNuHP3g6d7MKDBCDJYhjjQ9gKzSO4d5Zc5I_h08BHTNqKfMX_4F7wpG7I6cW7xTHB8xhMHu92uMTb2rdd3R2S5RGjnIRvKSy2OSSu8aQvpkVuna8TsfUTuDw5vliuslRCISuFoOtM6kpT5bWqgqhkXiJ-KiT3kuLh5iIgfHCorSmttApBuLLiYZ47zyrFHXMFfwqTpm3CcyCCF4p5jfgFMZYX3igpfcAnRoY7JuQU3oyCszcDU4YdQ8iubRRzLHlpbB9Hp6egR9naMQcUtVbo0hbqLLNdbqn9a5qnIH_2_GOlWDQC_3zjq3EKLW6h6BdxTWjvOptHhg1EzptbKI1AVhk-hWfD3P_6wkhuo3P54j9H9RLu9_6pPjxwDybr27uwjzBnXRzA9tvv7CAt5h-Sqvi5
link.rule.ids 315,786,790,4521,24144,27955,27956,45618,45712
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwELVKkYAL4psFSn3gRsM68df6WC0tW-j2wlbqAclyYkcKapOq2SJO_HZmHAeo0HJAyiFKnMQZOzMvmuc3hLwpcy4qo13mqwpFtQ3PHMTFzOduVpgZq4zCxcnLE7U4FR_P5NkWmY9rYZBWmXz_4NOjt05Hpsma08ummX7GyAPRRTGDmjXC3CK3EQ0gr-vdjz95HrHmGrbOsHlaOTOQvKrz5iKJVmJSQm-KTpvQZ4xChw_I_QQf6f7Qw4dkK7SPyJ1lSpA_Jl8GNWLa1fQb_AVHs9OmpUerD_sHFPaRSo5ne5jgXeO7vun36Px9zjgN3xMptt2jrvU0ltKiV843Sdb6CTk9PFjNF1kqoJBVQrB1JnWtmfJa1UHUsqgAPZWSe8lgczMRADw48NWM1VqFIFxV8zArnM9rxV3uSv6UbLddG54TKnipcq8BvQDC8sIbJaUPcEfUt8uFnJC3o-Hs5aCTYUcC2VeLZsaCl8ZGFp2eED3a1o4rQMFnhT59QL3NbV9YZv8a5AmRv668MU8shIB_PnF3HEILHxBmRVwbuuveFqivAbh5cwulAcYqwyfk2TD2v98QpW10IV_8Z692yd3Fanlsj49OPr0k92KmKhIFX5Ht9dV12AHAsy5fxwn9E8Sn-Y4
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effect+of+variation+in+ITGAE+on+risk+of+sarcoidosis%2C+CD103+expression%2C+and+chest+radiography&rft.jtitle=Clinical+immunology+%28Orlando%2C+Fla.%29&rft.au=Heron%2C+M&rft.au=Grutters%2C+J+C&rft.au=Van+Moorsel%2C+C+H+M&rft.au=Ruven%2C+H+J+T&rft.date=2009-10-01&rft.eissn=1521-7035&rft.volume=133&rft.issue=1&rft.spage=117&rft_id=info:doi/10.1016%2Fj.clim.2009.06.007&rft_id=info%3Apmid%2F19604725&rft.externalDocID=19604725
thumbnail_m http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F15216616%2FS1521661609X00100%2Fcov150h.gif