Hemodynamic Phenotyping of Pulmonary Hypertension in Left Heart Failure

• Published in: Circulation. Heart failure Vol. 10; no. 9
• Main Authors: Naeije, Robert, Gerges, Mario, Vachiery, Jean-Luc, Caravita, Sergio, Gerges, Christian, Lang, Irene M.
• Format: Journal Article
• Language: English
• Published: United States 01.09.2017
• Subjects: Arterial Pressure; Exercise Tolerance; Heart Failure - complications; Heart Failure - diagnosis; Heart Failure - mortality; Heart Failure - physiopathology; Humans; Hypertension, Pulmonary - diagnosis; Hypertension, Pulmonary - etiology; Hypertension, Pulmonary - mortality; Hypertension, Pulmonary - physiopathology; Phenotype; Predictive Value of Tests; Prognosis; Pulmonary Artery - physiopathology; Pulmonary Veins - physiopathology; Pulmonary Ventilation; Pulmonary Wedge Pressure; Risk Factors; Severity of Illness Index; Vascular Resistance; Vascular Stiffness; Venous Pressure; Ventricular Function, Left; Ventricular Function, Right; heart failure; ejection fraction; pulmonary vascular gradient; right ventricle; pulmonary hypertension; pulmonary compliance; pulmonary vascular resistance

Increased pulmonary venous pressure secondary to left heart disease is the most common cause of pulmonary hypertension (PH). The diagnosis of PH due to left heart disease relies on a clinical probability assessment followed by the invasive measurements of a mean pulmonary artery pressure (PAP) ≥25 m...