Time-dependent effect of chlorhexidine surgical prep

• Published in: The Journal of hospital infection Vol. 79; no. 4; pp. 313 - 316
• Main Authors: Stinner, D.J, Krueger, C.A, Masini, B.D, Wenke, J.C
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.12.2011; Elsevier
• Subjects: Anti-Infective Agents, Local - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiseptics; Bacterial Load - methods; Biological and medical sciences; Chlorhexidine; Chlorhexidine - pharmacology; Culture Media - chemistry; Dose-Response Relationship, Drug; Drug Stability; General aspects; Human infectious diseases. Experimental studies and models; Infectious Disease; Infectious diseases; Medical sciences; Pharmacology. Drug treatments; Staphylococcus aureus - drug effects; Surgical site infection; Time Factors; Surgical site infection; Chlorhexidine; Surgical wound; Nosocomial infection; Biguanides; Treatment; Surgery; Antiseptic; Guanidines; Disinfecting agent; Public health

Summary Despite continued advances in preoperative preventive measures and aseptic technique, surgical site infections remain a problem. The purpose of this study was to evaluate the time-dependent effectiveness of chlorhexidine, a common surgical preparation solution, at various concentrations. Aga...