Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression - Löfgren, Susanne; Baldwin, R. Michael; Hiratsuka, Masahiro; Lindqvist, Annelie; Carlberg, Anne; Sim, Sarah C.; Schülke, Meint; Snait, Michael; Edenro, Anne; Fransson-Steen, Ronny; Terelius, Ylva; Ingelman-Sundberg, Magnus (Drug metabolism and disposition, 2008)
Keywords: Animals; Aryl Hydrocarbon Hydroxylases - genetics; Biological and medical sciences; Cytochrome P-450 CYP2C19; Female; Gene Dosage; Gene Expression; Humans; Male; Medical sciences; Mephenytoin - metabolism; Mice; Mice, Transgenic - genetics; Microsomes - metabolism; Omeprazole; Pharmacology. Drug treatments; RNA, Messenger - metabolism; Sex Characteristics; Tissue Distribution; Characterization; Human; Vertebrata; Mammalia; Mouse; Enzyme; Isozyme; Cytochrome P450; Rodentia; Transgenic animal; Sexual dimorphism; Gene expression