Fyn Is Downstream of the HGF/MET Signaling Axis and Affects Cellular Shape and Tropism in PC3 Cells - Jensen, Ana R.; David, Saito Y.; Liao, Chuanhong; Dai, Jinlu; Keller, Evan T.; Al-Ahmadie, Hikmat; Dakin-Haché, Kelly; Usatyuk, Peter; Sievert, Margarit F.; Paner, Gladell P.; Yala, Soheil; Cervantes, Gustavo M.; et al. (Clinical cancer research, 2011)
Keywords: Adenocarcinoma - genetics; Adenocarcinoma - metabolism; Adenocarcinoma - pathology; Animals; Antineoplastic agents; Biological and medical sciences; Cell Line, Tumor; Cell Movement - drug effects; Cell Movement - genetics; Cell Shape - drug effects; Cell Shape - genetics; Gene Expression Regulation, Neoplastic - drug effects; Hepatocyte Growth Factor - genetics; Hepatocyte Growth Factor - metabolism; Humans; Male; Medical sciences; Mice; Mice, Nude; Neoplasm Metastasis; Pharmacology. Drug treatments; Prostatic Neoplasms - genetics; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Proto-Oncogene Proteins c-fyn - antagonists & inhibitors; Proto-Oncogene Proteins c-fyn - genetics; Proto-Oncogene Proteins c-fyn - metabolism; Proto-Oncogene Proteins c-fyn - physiology; Proto-Oncogene Proteins c-met - genetics; Proto-Oncogene Proteins c-met - metabolism; Receptors, Growth Factor - genetics; Receptors, Growth Factor - metabolism; RNA, Small Interfering - pharmacology; Signal Transduction - drug effects; Signal Transduction - genetics; Signal Transduction - physiology; Tropism - drug effects; Tropism - genetics; Xenograft Model Antitumor Assays; Tropism; Signal transduction; Shape; Hepatocyte growth factor; Cell; In vitro; Protooncogene; Tumor suppressor gene