H5N1 Vaccine–Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem - Wheatley, Adam K; Whittle, James R R; Lingwood, Daniel; Kanekiyo, Masaru; Yassine, Hadi M; Ma, Steven S; Narpala, Sandeep R; Prabhakaran, Madhu S; Matus-Nicodemos, Rodrigo A; Bailer, Robert T; Nabel, Gary J; Graham, Barney S; et al. (The Journal of immunology (1950), 2015)
Keywords: Amino Acid Sequence; Antibodies, Neutralizing - biosynthesis; Antibodies, Neutralizing - blood; Antibodies, Viral - biosynthesis; Antibodies, Viral - blood; Antigens, Viral - chemistry; Antigens, Viral - genetics; Antigens, Viral - immunology; B-Lymphocytes - cytology; B-Lymphocytes - immunology; B-Lymphocytes - virology; Epitopes - chemistry; Epitopes - genetics; Epitopes - immunology; Genetic Loci - immunology; Hemagglutinin Glycoproteins, Influenza Virus - chemistry; Hemagglutinin Glycoproteins, Influenza Virus - genetics; Hemagglutinin Glycoproteins, Influenza Virus - immunology; Humans; Immunologic Memory; Influenza A Virus, H5N1 Subtype - chemistry; Influenza A Virus, H5N1 Subtype - immunology; Influenza Vaccines - administration & dosage; Influenza Vaccines - genetics; Influenza Vaccines - immunology; Influenza, Human - blood; Influenza, Human - immunology; Influenza, Human - prevention & control; Influenza, Human - virology; Molecular Sequence Data; Recombinant Proteins - chemistry; Recombinant Proteins - genetics; Recombinant Proteins - immunology; Single-Chain Antibodies - chemistry; Single-Chain Antibodies - genetics; Single-Chain Antibodies - immunology; Vaccination; Vaccines, DNA; Vaccines, Inactivated