HIV-1 Single-Stranded RNA Induces CXCL13 Secretion in Human Monocytes via TLR7 Activation and Plasmacytoid Dendritic Cell–Derived Type I IFN - Cohen, Kristen W; Dugast, Anne-Sophie; Alter, Galit; McElrath, M Juliana; Stamatatos, Leonidas (The Journal of immunology (1950), 2015)
Keywords: Anti-Retroviral Agents - therapeutic use; Cells, Cultured; Chemokine CXCL13 - genetics; Chemokine CXCL13 - immunology; Chemokine CXCL13 - secretion; Cohort Studies; Dendritic Cells - immunology; Dendritic Cells - metabolism; Flow Cytometry; Gene Expression - immunology; HIV Infections - blood; HIV Infections - drug therapy; HIV Infections - immunology; HIV-1 - genetics; HIV-1 - immunology; Host-Pathogen Interactions - drug effects; Host-Pathogen Interactions - immunology; Human immunodeficiency virus; Human immunodeficiency virus 1; Humans; Imidazoles - pharmacology; Interferon-alpha - immunology; Interferon-alpha - metabolism; Interferon-alpha - pharmacology; Lentivirus; Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - immunology; Leukocytes, Mononuclear - virology; Monocytes - immunology; Monocytes - metabolism; Monocytes - virology; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral - genetics; RNA, Viral - immunology; Toll-Like Receptor 7 - agonists; Toll-Like Receptor 7 - immunology; Toll-Like Receptor 7 - metabolism; Viremia - drug therapy; Viremia - immunology; Viremia - virology