Pb(NO3)2 induces cell apoptosis through triggering of reactive oxygen species accumulation and disruption of mitochondrial function via SIRT3/SOD2 pathways - Lin, Hui‐Wen; Lee, Hsiang‐Lin; Shen, Ting‐Jing; Ho, Meng‐Ting; Lee, Yi‐Ju; Wang, Inga; Lin, Ching‐Pin; Chang, Yuan‐Yen (Environmental toxicology, 2024)
Keywords: Accumulation; Apoptosis; Caspase-3; cell apoptosis; Cell death; Cells; Disulfide reductase; ecotoxicology; Glutathione; glutathione-disulfide reductase; Humans; Hydrogen peroxide; Lead; Lung cancer; Lung carcinoma; lung neoplasms; Lungs; Membrane potential; Mitochondria; Mitochondria - metabolism; mitochondrial; mitochondrial membrane; Mortality; Neoplasms; oxidoreductive activity; Oxygen; Pb(NO3)2; Reactive oxygen species; Reactive Oxygen Species - metabolism; Reductases; ROS; Sirtuin 3 - metabolism; sirtuins; Superoxide dismutase; Superoxide Dismutase - metabolism; toxicity; cell apoptosis; mitochondrial; oxidoreductive activity; Pb(NO3)2; ROS