Automating unambiguous NOE data usage in NVR for NMR protein structure-based assignments

• Published in: Journal of bioinformatics and computational biology Vol. 13; no. 6; p. 1550020
• Main Authors: Akhmedov, Murodzhon, Çatay, Bülent, Apaydın, Mehmet Serkan
• Format: Journal Article
• Language: English
• Published: Singapore 01.12.2015
• Subjects: Algorithms; Computational Biology - methods; Magnetic Resonance Spectroscopy - methods; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular - methods; Protein Conformation; Proteins - chemistry; combinatorial optimization; NMR protein structure-based assignments; ant colony optimization; NOE

Nuclear Magnetic Resonance (NMR) Spectroscopy is an important technique that allows determining protein structure in solution. An important problem in protein structure determination using NMR spectroscopy is the mapping of peaks to corresponding amino acids, also known as the assignment problem. St...