Acrolein Can Cause Cardiovascular Disease: A Review

• Published in: Cardiovascular toxicology Vol. 17; no. 3; pp. 227 - 236
• Main Authors: Henning, Robert J., Johnson, Giffe T., Coyle, Jayme P., Harbison, Raymond D.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.07.2017; Springer; Springer Nature B.V
• Subjects: Acrolein; Acrolein - adverse effects; Animals; Apoptosis; Biomedical and Life Sciences; Biomedicine; Burning; Cardiology; Cardiomyopathy; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - chemically induced; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - metabolism; Chronic exposure; Cigarette Smoking - adverse effects; Cigarette Smoking - epidemiology; Cigarettes; Cooking; Environmental Pollutants - adverse effects; Epidemiology; Food; Fuels; Gasoline; Heart diseases; Humans; Inhalation; Nitric oxide; Nitric-oxide synthase; Oils & fats; Organic chemicals; Oxidative Stress - physiology; Oxygen; Pharmacology/Toxicology; Phosphorylation; Protein adducts; Skin; Toxicity; Vasoconstriction; Water in agriculture; Water-supply, Agricultural; Free oxygen radicals; Protein adducts; Glutathione depletion; Unsaturated aldehydes

Acrolein is a highly reactive unsaturated aldehyde that is formed during the burning of gasoline and diesel fuels, cigarettes, woods and plastics. In addition, acrolein is generated during the cooking or frying of food with fats or oils. Acrolein is also used in the synthesis of many organic chemica...