Germline Lysine-Specific Demethylase 1 ( LSD1/KDM1A ) Mutations Confer Susceptibility to Multiple Myeloma - Wei, Xiaomu; Calvo-Vidal, M. Nieves; Chen, Siwei; Wu, Gang; Revuelta, Maria V.; Sun, Jian; Zhang, Jinghui; Walsh, Michael F.; Nichols, Kim E.; Joseph, Vijai; Snyder, Carrie; Vachon, Celine M.; et al. (Cancer research (Chicago, Ill.), 2018)
Keywords: Age; Animals; Benign monoclonal gammopathy; Cancer; Cell Line, Tumor; Cell self-renewal; Cyclin D2 - biosynthesis; Etiology; Gene expression; Genes, Tumor Suppressor; Genetic Predisposition to Disease - genetics; Germ Cells - pathology; Hematopoietic stem cells; Histone Demethylases - antagonists & inhibitors; Histone Demethylases - genetics; Histone H3; Histones - metabolism; Humans; Immune response; Lymphocytes B; Lysine; Male; Mice; Mice, Inbred C57BL; Monoclonal Gammopathy of Undetermined Significance - genetics; Multiple myeloma; Multiple Myeloma - genetics; Mutation; Mutation, Missense - genetics; Myc protein; Paraproteins - analysis; Plasma; Plasma Cells - pathology; RNA Interference; RNA, Small Interfering - genetics; Stem cells; Transcription; Tumor suppressor genes