Methadone analgesia in the critically ill
Any patient who is discharged to an outpatient setting on methadone without a planned taper should be referred to a provider with experience using methadone in chronic pain management. Because the highest risk of death due to methadone therapy occurs around the time of initiation [7,9] (often due to...
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| Published in | Journal of critical care Vol. 36; p. 296 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.12.2016
Elsevier Limited |
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| Abstract | Any patient who is discharged to an outpatient setting on methadone without a planned taper should be referred to a provider with experience using methadone in chronic pain management. Because the highest risk of death due to methadone therapy occurs around the time of initiation [7,9] (often due to rapid upward titration by inexperienced prescribers), the risk of respiratory compromise while completing a methadone taper after discharge should be low. |
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| AbstractList | Any patient who is discharged to an outpatient setting on methadone without a planned taper should be referred to a provider with experience using methadone in chronic pain management. Because the highest risk of death due to methadone therapy occurs around the time of initiation [7,9] (often due to rapid upward titration by inexperienced prescribers), the risk of respiratory compromise while completing a methadone taper after discharge should be low. |
| Author | Elefritz, Jessica L., PharmD Lyaker, Michael R., MD Murphy, Claire V., PharmD, BCPS |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27491562$$D View this record in MEDLINE/PubMed |
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| Keywords | mortality critical care intensive care unit pain management methadone analgesia Critical care Analgesia Methadone Mortality Intensive care unit Pain management |
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| References | Elefritz, Murphy, Papadimos, Lyaker (bb0040) 2016; 34 Lev, Petro, Lee, Lee, Lucas, Castillo (bb0005) 2015; 257 Ojanperä, Kriikku, Vuori (bb0010) 2016; 1–8 (bb0015) 2012; 61 Vignali, Toombs (bb0030) 2015 Center for Substance Abuse Treatment (bb0035) 2004 Buster, van Brussel, van den Brink (bb0045) 2002; 97 Manchikanti, Abdi, Balog (bb0020) 2012; 15 Manchikanti, Abdi, Atluri (bb0025) 2012; 15 27472993 - J Crit Care. 2016 Dec;36:295 Vignali (10.1016/j.jcrc.2016.07.009_rf0030) 2015 Center for Substance Abuse Treatment (10.1016/j.jcrc.2016.07.009_bb0035) 2004 Manchikanti (10.1016/j.jcrc.2016.07.009_bb0020) 2012; 15 Elefritz (10.1016/j.jcrc.2016.07.009_bb0040) 2016; 34 Buster (10.1016/j.jcrc.2016.07.009_bb0045) 2002; 97 Ojanperä (10.1016/j.jcrc.2016.07.009_bb0010) 2016; 1–8 (10.1016/j.jcrc.2016.07.009_bb0015) 2012; 61 Lev (10.1016/j.jcrc.2016.07.009_bb0005) 2015; 257 Manchikanti (10.1016/j.jcrc.2016.07.009_bb0025) 2012; 15 Toombs (10.1016/j.jcrc.2016.07.009_rf0035) 2005 |
| References_xml | – volume: 34 start-page: 84 year: 2016 end-page: 88 ident: bb0040 article-title: Methadone analgesia in the critically ill publication-title: J Crit Care contributor: fullname: Lyaker – volume: 257 start-page: 347 year: 2015 end-page: 352 ident: bb0005 article-title: Methadone related deaths compared to all prescription related deaths publication-title: Forensic Sci Int contributor: fullname: Castillo – volume: 61 start-page: 493 year: 2012 end-page: 497 ident: bb0015 publication-title: CDC vital signs: risk for overdose from methadone used for pain relief—United States, 1999-2010 – year: 2004 ident: bb0035 article-title: Methadone-associated mortality: report of a National Assessment, May 8–9, 2003 publication-title: SAMHSA publication no. 04-3904 contributor: fullname: Center for Substance Abuse Treatment – volume: 15 start-page: S67 year: 2012 end-page: 116 ident: bb0025 article-title: American Society of Interventional Pain Physicians (ASIPP) guidelines for responsible opioid prescribing in chronic non-cancer pain: part II—evidence assessment publication-title: Guidance Pain Physician contributor: fullname: Atluri – year: 2015 ident: bb0030 article-title: Methadone-related deaths. A ten year overview contributor: fullname: Toombs – volume: 1–8 year: 2016 ident: bb0010 article-title: Fatal toxicity index of medicinal drugs based on a comprehensive toxicology database publication-title: Int J Legal Med contributor: fullname: Vuori – volume: 15 start-page: S1 year: 2012 end-page: 65 ident: bb0020 article-title: American Society of Interventional Pain Physicians (ASIPP) guidelines for responsible opioid prescribing in chronic non-cancer pain: part I—evidence assessment publication-title: Pain Physician contributor: fullname: Balog – volume: 97 start-page: 993 year: 2002 end-page: 1001 ident: bb0045 article-title: An increase in overdose mortality during the first 2 publication-title: Addiction contributor: fullname: van den Brink – volume: 97 start-page: 993 issue: 8 year: 2002 ident: 10.1016/j.jcrc.2016.07.009_bb0045 article-title: An increase in overdose mortality during the first 2weeks after re-entering or reentering methadone treatment in Amsterdam publication-title: Addiction doi: 10.1046/j.1360-0443.2002.00179.x contributor: fullname: Buster – volume: 1–8 year: 2016 ident: 10.1016/j.jcrc.2016.07.009_bb0010 article-title: Fatal toxicity index of medicinal drugs based on a comprehensive toxicology database publication-title: Int J Legal Med contributor: fullname: Ojanperä – volume: 257 start-page: 347 year: 2015 ident: 10.1016/j.jcrc.2016.07.009_bb0005 article-title: Methadone related deaths compared to all prescription related deaths publication-title: Forensic Sci Int doi: 10.1016/j.forsciint.2015.09.021 contributor: fullname: Lev – volume: 34 start-page: 84 year: 2016 ident: 10.1016/j.jcrc.2016.07.009_bb0040 article-title: Methadone analgesia in the critically ill publication-title: J Crit Care doi: 10.1016/j.jcrc.2016.03.023 contributor: fullname: Elefritz – volume: 15 start-page: S67 issue: 3 Suppl. year: 2012 ident: 10.1016/j.jcrc.2016.07.009_bb0025 article-title: American Society of Interventional Pain Physicians (ASIPP) guidelines for responsible opioid prescribing in chronic non-cancer pain: part II—evidence assessment publication-title: Guidance Pain Physician contributor: fullname: Manchikanti – volume: 61 start-page: 493 year: 2012 ident: 10.1016/j.jcrc.2016.07.009_bb0015 publication-title: MMWR Morbidity Mortal Wkly Rep – volume: 15 start-page: S1 issue: 3 Suppl. year: 2012 ident: 10.1016/j.jcrc.2016.07.009_bb0020 article-title: American Society of Interventional Pain Physicians (ASIPP) guidelines for responsible opioid prescribing in chronic non-cancer pain: part I—evidence assessment publication-title: Pain Physician doi: 10.36076/ppj.2012/15/E1 contributor: fullname: Manchikanti – year: 2004 ident: 10.1016/j.jcrc.2016.07.009_bb0035 article-title: Methadone-associated mortality: report of a National Assessment, May 8–9, 2003 contributor: fullname: Center for Substance Abuse Treatment – year: 2015 ident: 10.1016/j.jcrc.2016.07.009_rf0030 contributor: fullname: Vignali – year: 2005 ident: 10.1016/j.jcrc.2016.07.009_rf0035 contributor: fullname: Toombs |
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| Title | Methadone analgesia in the critically ill |
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