Canthinone alkaloids are novel protein tyrosine phosphatase 1B inhibitors - Sasaki, Tatsunori; Li, Wei; Higai, Koji; Koike, Kazuo (Bioorganic & medicinal chemistry letters, 2015)
Keywords: Biological Products - chemistry; Biological Products - pharmacology; Carbolines - chemistry; Carbolines - pharmacology; Dose-Response Relationship, Drug; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - pharmacology; Hep G2 Cells; Humans; Indole Alkaloids - chemistry; Indole Alkaloids - pharmacology; Molecular Docking Simulation; Molecular Structure; Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism; Structure-Activity Relationship; Picrasidine L; Protein tyrosine phosphatase 1B; Canthinone; Diabetes