The 6-min walk distance in healthy subjects: reference standards from seven countries
The 6-min walk distance (6MWD) predicted values have been derived from small cohorts mostly from single countries. The aim of the present study was to investigate differences between countries and identify new reference values to improve 6MWD interpretation. We studied 444 subjects (238 males) from...
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| Published in | The European respiratory journal Vol. 37; no. 1; pp. 150 - 156 |
|---|---|
| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Leeds
Maney
01.01.2011
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The 6-min walk distance (6MWD) predicted values have been derived from small cohorts mostly from single countries. The aim of the present study was to investigate differences between countries and identify new reference values to improve 6MWD interpretation.
We studied 444 subjects (238 males) from seven countries (10 centres) ranging 40–80 yrs of age. We measured 6MWD, height, weight, spirometry, heart rate (HR), maximum HR (HR max ) during the 6-min walk test/the predicted maximum HR (HR max % pred), Borg dyspnoea score and oxygen saturation.
The mean± sd 6MWD was 571±90 m (range 380–782 m). Males walked 30 m more than females (p<0.001). A multiple regression model for the 6MWD included age, sex, height, weight and HR max % pred (adjusted r 2 = 0.38; p<0.001), but there was variability across centres (adjusted r 2 = 0.09–0.73) and its routine use is not recommended. Age had a great impact in 6MWD independent of the centres, declining significantly in the older population (p<0.001). Age-specific reference standards of 6MWD were constructed for male and female adults.
In healthy subjects, there were geographic variations in 6MWD and caution must be taken when using existing predictive equations. The present study provides new 6MWD standard curves that could be useful in the care of adult patients with chronic diseases. |
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| AbstractList | The 6-min walk distance (6MWD) predicted values have been derived from small cohorts mostly from single countries. The aim of the present study was to investigate differences between countries and identify new reference values to improve 6MWD interpretation.
We studied 444 subjects (238 males) from seven countries (10 centres) ranging 40–80 yrs of age. We measured 6MWD, height, weight, spirometry, heart rate (HR), maximum HR (HR max ) during the 6-min walk test/the predicted maximum HR (HR max % pred), Borg dyspnoea score and oxygen saturation.
The mean± sd 6MWD was 571±90 m (range 380–782 m). Males walked 30 m more than females (p<0.001). A multiple regression model for the 6MWD included age, sex, height, weight and HR max % pred (adjusted r 2 = 0.38; p<0.001), but there was variability across centres (adjusted r 2 = 0.09–0.73) and its routine use is not recommended. Age had a great impact in 6MWD independent of the centres, declining significantly in the older population (p<0.001). Age-specific reference standards of 6MWD were constructed for male and female adults.
In healthy subjects, there were geographic variations in 6MWD and caution must be taken when using existing predictive equations. The present study provides new 6MWD standard curves that could be useful in the care of adult patients with chronic diseases. The 6-min walk distance (6MWD) predicted values have been derived from small cohorts mostly from single countries. The aim of the present study was to investigate differences between countries and identify new reference values to improve 6MWD interpretation. We studied 444 subjects (238 males) from seven countries (10 centres) ranging 40-80 yrs of age. We measured 6MWD, height, weight, spirometry, heart rate (HR), maximum HR (HR(max)) during the 6-min walk test/the predicted maximum HR (HR(max) % pred), Borg dyspnoea score and oxygen saturation. The mean ± sd 6MWD was 571 ± 90 m (range 380-782 m). Males walked 30 m more than females (p < 0.001). A multiple regression model for the 6MWD included age, sex, height, weight and HR(max) % pred (adjusted r² = 0.38; p < 0.001), but there was variability across centres (adjusted r² = 0.09-0.73) and its routine use is not recommended. Age had a great impact in 6MWD independent of the centres, declining significantly in the older population (p < 0.001). Age-specific reference standards of 6MWD were constructed for male and female adults. In healthy subjects, there were geographic variations in 6MWD and caution must be taken when using existing predictive equations. The present study provides new 6MWD standard curves that could be useful in the care of adult patients with chronic diseases. The 6-min walk distance (6MWD) predicted values have been derived from small cohorts mostly from single countries. The aim of the present study was to investigate differences between countries and identify new reference values to improve 6MWD interpretation. We studied 444 subjects (238 males) from seven countries (10 centres) ranging 40-80 yrs of age. We measured 6MWD, height, weight, spirometry, heart rate (HR), maximum HR (HR(max)) during the 6-min walk test/the predicted maximum HR (HR(max) % pred), Borg dyspnoea score and oxygen saturation. The mean ± sd 6MWD was 571 ± 90 m (range 380-782 m). Males walked 30 m more than females (p < 0.001). A multiple regression model for the 6MWD included age, sex, height, weight and HR(max) % pred (adjusted r² = 0.38; p < 0.001), but there was variability across centres (adjusted r² = 0.09-0.73) and its routine use is not recommended. Age had a great impact in 6MWD independent of the centres, declining significantly in the older population (p < 0.001). Age-specific reference standards of 6MWD were constructed for male and female adults. In healthy subjects, there were geographic variations in 6MWD and caution must be taken when using existing predictive equations. The present study provides new 6MWD standard curves that could be useful in the care of adult patients with chronic diseases.The 6-min walk distance (6MWD) predicted values have been derived from small cohorts mostly from single countries. The aim of the present study was to investigate differences between countries and identify new reference values to improve 6MWD interpretation. We studied 444 subjects (238 males) from seven countries (10 centres) ranging 40-80 yrs of age. We measured 6MWD, height, weight, spirometry, heart rate (HR), maximum HR (HR(max)) during the 6-min walk test/the predicted maximum HR (HR(max) % pred), Borg dyspnoea score and oxygen saturation. The mean ± sd 6MWD was 571 ± 90 m (range 380-782 m). Males walked 30 m more than females (p < 0.001). A multiple regression model for the 6MWD included age, sex, height, weight and HR(max) % pred (adjusted r² = 0.38; p < 0.001), but there was variability across centres (adjusted r² = 0.09-0.73) and its routine use is not recommended. Age had a great impact in 6MWD independent of the centres, declining significantly in the older population (p < 0.001). Age-specific reference standards of 6MWD were constructed for male and female adults. In healthy subjects, there were geographic variations in 6MWD and caution must be taken when using existing predictive equations. The present study provides new 6MWD standard curves that could be useful in the care of adult patients with chronic diseases. |
| Author | Pinto-Plata, V. Celli, B.R. Cote, C. Marin, J.M. Lopez, M.V. Barria, P. de Torres, J.P. Casanova, C. Jardim, J. Aguirre-Jaime, A. Montes de Oca, M. Casas, A. |
| Author_xml | – sequence: 1 givenname: C. surname: Casanova fullname: Casanova, C. – sequence: 2 givenname: B.R. surname: Celli fullname: Celli, B.R. – sequence: 3 givenname: P. surname: Barria fullname: Barria, P. – sequence: 4 givenname: A. surname: Casas fullname: Casas, A. – sequence: 5 givenname: C. surname: Cote fullname: Cote, C. – sequence: 6 givenname: J.P. surname: de Torres fullname: de Torres, J.P. – sequence: 7 givenname: J. surname: Jardim fullname: Jardim, J. – sequence: 8 givenname: M.V. surname: Lopez fullname: Lopez, M.V. – sequence: 9 givenname: J.M. surname: Marin fullname: Marin, J.M. – sequence: 10 givenname: M. surname: Montes de Oca fullname: Montes de Oca, M. – sequence: 11 givenname: V. surname: Pinto-Plata fullname: Pinto-Plata, V. – sequence: 12 givenname: A. surname: Aguirre-Jaime fullname: Aguirre-Jaime, A. |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23823521$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/20525717$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/j.rmed.2006.01.001 10.1164/rccm.200607-883OC 10.1055/s-2007-1009415 10.1016/S0002-8703(03)00119-4 10.1378/chest.08-0520 10.1183/09031936.00104507 10.1378/chest.123.2.387 10.1164/ajrccm/144.5.1202 10.1249/00005768-198205000-00012 10.1378/chest.108.2.452 10.1378/chest.128.1.55 10.1164/ajrccm.161.2.9906015 10.1164/rccm.200407-867OC 10.1016/j.rmed.2005.08.003 10.1164/rccm.200604-488OC 10.1016/0895-4356(94)90129-5 10.1016/S1388-9842(02)00244-1 10.1164/rccm.200407-855OC 10.1183/09031936.00071506 10.1164/ajrccm.166.1.at1102 10.1164/ajrccm.158.5.9710086 10.1183/09031936.03.00034603 10.1378/chest.128.4.2012 10.1097/00008483-200103000-00005 10.1183/09031936.00140507 10.1164/ajrccm.155.4.9105067 10.1053/apmr.2002.33227 10.1034/j.1399-3003.1999.14b06.x |
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| Title | The 6-min walk distance in healthy subjects: reference standards from seven countries |
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