TGA/Chemometric Test Is Able to Detect the Presence of a Rare Hemoglobin Variant Hb Bibba

• Published in: Frontiers in molecular biosciences Vol. 6; p. 101
• Main Authors: Risoluti, Roberta, Caprari, Patrizia, Gullifa, Giuseppina, Diana, Loretta, Luciani, Matteo, Amato, Antonio, Materazzi, Stefano
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 01.10.2019
• Subjects: chemometrics; Hb Bibba; hemoglobin defect; Molecular Biosciences; screening; thermogravimetric analysis

In this study the TGA/Chemometric test was applied for diagnosis of a case of congenital hemolytic anemia for which the common first level diagnostic tests were not able to find the erythrocyte congenital defect. A 6 years old girl presented chronic hemolytic anemia characterized by hyperbilirubinem...