Efficacy and Safety of Ferrous Bisglycinate and Folinic Acid in the Control of Iron Deficiency in Pregnant Women: A Randomized, Controlled Trial

• Published in: Nutrients Vol. 14; no. 3; p. 452
• Main Authors: Bumrungpert, Akkarach, Pavadhgul, Patcharanee, Piromsawasdi, Theera, Mozafari, M. R.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 20.01.2022; MDPI
• Subjects: absorption; Acids; Anemia; Anemia, Iron-Deficiency - blood; Anemia, Iron-Deficiency - drug therapy; Bioavailability; biomarkers; Biomarkers - blood; Blood pressure; blood serum; breakfast; Clinical trials; Constipation; Diarrhea; dietary supplements; Female; ferritin; Ferrous Compounds - therapeutic use; fumarates; Functional foods & nutraceuticals; Glycine - therapeutic use; Hematology; Hemoglobin; Humans; Iron; iron absorption; Iron Deficiencies - blood; Iron Deficiencies - drug therapy; Leucovorin - therapeutic use; nausea; pain; Pregnancy; Pregnancy Complications - blood; Pregnancy Complications - drug therapy; Public health; Quality of life; reticulocytes; School dropouts; Statistical analysis; taste; Testing laboratories; transferrin; Vitamin B; Womens health; Thailand; pregnant women; absorption; folinic acid; side effects; iron deficiency; ferrous bisglycinate; iron status

Iron deficiency in pregnancy is a major public health problem that causes maternal complications. The objective of this randomized, controlled trial was to examine the bioavailability, efficacy, and safety of oral ferrous bisglycinate plus folinic acid supplementation in pregnant women with iron def...