Systematic Review and Meta-Analysis of SERPINE1 4G/5G Insertion/Deletion Variant With Circulating Lipid Levels

• Published in: Frontiers in cardiovascular medicine Vol. 9; p. 859979
• Main Authors: Luo, Zhi, Liu, Yang, Li, Hang, Zhou, Yawen, Peng, Yuanyuan, Lin, Xuan, Fang, Ying, Wan, Jing, Wei, Baozhu
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 23.06.2022
• Subjects: Asian; Cardiovascular Medicine; coronary artery disease; lipid; polymorphism; rs1799889

Recent studies have shown that the 4G/5G insertion/deletion variant of SERPINE1 (rs1799889) is closely linked to coronary artery disease (CAD). This study aims to clarify the effects of the rs1799889 variant on lipid levels and to insight into the mechanisms underlying the rs1799889 variant and CAD....