Cell-Based Measures of Viral Persistence Are Associated With Immune Activation and Programmed Cell Death Protein 1 (PD-1)—Expressing CD4+T cells - Hatano, Hiroyu; Jain, Vivek; Hunt, Peter W.; Lee, Tzong-Hae; Sinclair, Elizabeth; Do, Tri D.; Hoh, Rebecca; Martin, Jeffrey N.; McCune, Joseph M.; Hecht, Frederick; Busch, Michael P.; Deeks, Steven G. (The Journal of infectious diseases, 2013)
Keywords: Adult; AIDS; Antiretroviral Therapy, Highly Active; Antiretrovirals; Biological and medical sciences; Blood plasma; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes - immunology; DNA; DNA, Viral - drug effects; Female; Fundamental and applied biological sciences. Psychology; Highly active antiretroviral therapy; HIV; HIV - drug effects; HIV 1; HIV Infections - drug therapy; HIV Infections - immunology; HIV Infections - virology; HIV/AIDS; Humans; Immunity, Cellular - drug effects; Infectious diseases; Lymphocyte Activation - drug effects; Lymphocyte Activation - immunology; Major and Brief Reports; Male; Medical sciences; Microbiology; Middle Aged; Programmed Cell Death 1 Receptor - blood; Proviruses - drug effects; RNA; RNA, Viral - blood; T lymphocytes; Virology; Infection; CD4 T lymphocyte; Protein; Apoptosis; D-dimer; 2-LTR circles; HIV; ongoing viral replication; raltegravir intensification