Streamlined Multi-Attribute Assessment of an Array of Clinical-Stage Antibodies: Relationship Between Degradation and Stability - Pastrana, Belinda; Culyba, Elizabeth; Nieves, Sherly; Sazinsky, Stephen L.; Canto, Eduardo I.; Noda, Isao (Applied spectroscopy, 2025)
Keywords: asparagine and glutamine deamidation; 2T2D; two-dimensional correlation spectroscopy; quantum cascade laser microspectroscopy; 2D-COS; two-trace two-dimensional; protein stability; cation exchange; Biotherapeutic; extent of deamidation; protein aggregation; high-performance liquid chromatography; correlation spectroscopy; co-distribution correlation spectroscopy; HPLC