Altered brain gyrification in deficit and non-deficit schizophrenia

• Published in: Psychological medicine Vol. 49; no. 4; pp. 573 - 580
• Main Authors: Takayanagi, Yoichiro, Sasabayashi, Daiki, Takahashi, Tsutomu, Komori, Yuko, Furuichi, Atsushi, Kido, Mikio, Nishikawa, Yumiko, Nakamura, Mihoko, Noguchi, Kyo, Suzuki, Michio
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.03.2019
• Subjects: Adult; Apathy; Automation; Brain; Brain - abnormalities; Brain - diagnostic imaging; Brain - growth & development; Brain - pathology; Brain research; Case-Control Studies; Classification; Cortex; Cortex (insular); Cortex (parietal); Deficit syndrome; Emotional behavior; Female; Head injuries; Humans; Illnesses; Magnetic Resonance Imaging; Male; Medical research; Mental disorders; Negative symptoms; Neurodevelopmental disorders; Neuroimaging; NMR; Nuclear magnetic resonance; Occipital lobe; Original Articles; Patients; Prefrontal cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenia - pathology; Schizophrenic Psychology; local gyrification index; magnetic resonance imaging; Deficit schizophrenia; neurodevelopmental disorder; negative symptoms

Patients with the deficit form of schizophrenia (D-SZ) are characterized by severe primary negative symptoms and differ from patients with the non-deficit form of schizophrenia (ND-SZ) in several aspects. No study has measured brain gyrification, which is a potential marker of neurodevelopment, in D...