INPP4B inhibits glioma cell proliferation and immune escape via inhibition of the PI3K/AKT signaling pathway

• Published in: Frontiers in oncology Vol. 12; p. 983537
• Main Authors: Sun, Xiaoming, Chen, Yani, Tao, Xiaoyang, Zhang, Wenzi, Wang, Xinyu, Wang, Xianhui, Ruan, Zhihua, Chen, Zhuo
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 06.09.2022
• Subjects: glioma; immune escape; INPP4B; Oncology; PD-L1; PI3K/AKT signaling

INPP4B (Inositol polyphosphate 4-phosphatase type II) has been regarded as a suppressor of several human tumors, but its biological function, expression, and clinical significance in glioma tissues and cell lines are unclear. Notably, whether INPP4B participates in immune escape of glioma deserves u...