Exome of Radiation-induced Rat Mammary Carcinoma Shows Copy-number Losses and Mutations in Human-relevant Cancer Genes - MORIYAMA, HITOMI; DAINO, KAZUHIRO; ISHIKAWA, ATSUKO; IMAOKA, TATSUHIKO; NISHIMURA, MAYUMI; NISHIMURA, YUKIKO; TAKABATAKE, MASARU; MORIOKA, TAKAMITSU; INOUE, KAZUMASA; FUKUSHI, MASAHIRO; SHIMADA, YOSHIYA; KAKINUMA, SHIZUKO (Anticancer research, 2021)
Keywords: 1-Phosphatidylinositol 3-kinase; AKT protein; Animals; Biopsy; Breast cancer; Cancer; Cloning; Computational Biology - methods; DNA Copy Number Variations - radiation effects; DNA Methylation; DNA Mutational Analysis; Exome; Experiments; Female; Gamma rays; Genes; Genetic testing; Health risks; Humans; Immunohistochemistry; INDEL Mutation; Mammary gland; Mammary Neoplasms, Experimental - genetics; Mammary Neoplasms, Experimental - pathology; Mammary Neoplasms, Experimental - radiotherapy; Mutation; Mutation - radiation effects; Neoplasms, Radiation-Induced - genetics; Neoplasms, Radiation-Induced - pathology; Neutrons; Nuclear accidents & safety; Point mutation; Radiation; Radiation effects; Radiation, Ionizing; Rats; Rodents; Signal transduction; Statistical analysis; Tumorigenesis; Tumors; Whole Exome Sequencing; Whole genome sequencing; Wnt protein; β-Catenin; United States--US; Japan; Germany; breast cancer; Neutron; genomic aberrations