Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach

• Published in: Neurobiology of disease Vol. 186; p. 106281
• Main Authors: Maple-Grødem, Jodi, Ushakova, Anastasia, Pedersen, Kenn Freddy, Tysnes, Ole-Bjørn, Alves, Guido, Lange, Johannes
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.10.2023; Elsevier
• Subjects: Biomarkers; CSF; Parkinson's disease; Proximity extension assay; Biomarkers; Parkinson's disease; Proximity extension assay; CSF

Given the complexity of Parkinson's disease (PD), achieving acceptable diagnostic and prognostic accuracy will require the support of a panel of diverse biomarkers. We used Proximity extension assays to measure a panel of 92 proteins in CSF of 120 newly diagnosed PD patients and 45 control subj...