Silently transformable: the many ways bacteria conceal their built-in capacity of genetic exchange

• Published in: Current genetics Vol. 63; no. 3; pp. 451 - 455
• Main Authors: Attaiech, Laetitia, Charpentier, Xavier
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2017; Springer Nature B.V; Springer Verlag
• Subjects: Bacteria; Bacteriology; Biochemistry; Biological evolution; Biomedical and Life Sciences; Cell Biology; Chromosomes; Deoxyribonucleic acid; DNA; DNA, Bacterial - genetics; Evolution, Molecular; Exchanging; Gene expression; Gene Expression Regulation, Bacterial; genetic transformation; genome; homologous recombination; Homologous Recombination - genetics; Homology; Immunology; Legionella pneumophila; Legionella pneumophila - genetics; Legionnaires' disease bacterium; Life Sciences; Microbial Genetics and Genomics; Microbiology; Microbiology and Parasitology; non-coding RNA; phylogeny; Plant Sciences; Proteomics; Regulatory mechanisms (biology); Review; RNA, Small Untranslated - genetics; Transformation, Bacterial - genetics; Transformation, Genetic; Transformations; Virology; Competence; HGT; Silencing; Gene regulation; sRNA; Bacterial; Transformation; RNA; Gene Expression Regulation; Genetic; Homologous Recombination; Legionella pneumophila; Molecular; Small Untranslated; DNA; Evolution

Bacteria can undergo genetic transformation by actively integrating genetic information from phylogenetically related or unrelated organisms. The original function of natural transformation remains a subject of debate, but it is well established as a major player in genome evolution. Naturally trans...