Neuroprotective Effects of Fluoxetine Against Chronic Stress-Induced Neural Inflammation and Apoptosis: Involvement of the p38 Activity

• Published in: Frontiers in physiology Vol. 11; p. 351
• Main Authors: Zhao, Yuxiao, Shang, Pan, Wang, Meijian, Xie, Min, Liu, Jian
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 11.05.2020
• Subjects: apoptosis; depression; fluoxetine; neuroinflammation; neuroprotection; p38; Physiology

Depression is considered a widespread neuropsychiatric disease associated with neuronal injury within specific brain regions. Fluoxetine, a selective serotonin reuptake inhibitor, has been widely used in depressed patients. Recently, fluoxetine has demonstrated neuroprotective effects apart from the...