Predicting lncRNA-miRNA Interaction via Graph Convolution Auto-Encoder

• Published in: Frontiers in genetics Vol. 10; p. 758
• Main Authors: Huang, Yu-An, Huang, Zhi-An, You, Zhu-Hong, Zhu, Zexuan, Huang, Wen-Zhun, Guo, Jian-Xin, Yu, Chang-Qing
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 29.08.2019
• Subjects: computational prediction model; Genetics; graph convolution network; LncRNA–miRNA interactions; regulation network; system biology model

The interaction of miRNA and lncRNA is known to be important for gene regulations. However, the number of known lncRNA-miRNA interactions is still very limited and there are limited computational tools available for predicting new ones. Considering that lncRNAs and miRNAs share internal patterns in...