In vitro and in vivo Synergistic Effects of Florfenicol and Thiamphenicol in Combination Against Swine Actinobacillus pleuropneumoniae and Pasteurella multocida

• Published in: Frontiers in microbiology Vol. 10; p. 2430
• Main Authors: Rattanapanadda, Porjai, Kuo, Hung-Chih, Vickroy, Thomas W., Sung, Chi-Hsuan, Rairat, Tirawat, Lin, Tsai-Lu, Yeh, Sze-Yu, Chou, Chi-Chung
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 30.10.2019
• Subjects: Actinobacillus pleuropneumoniae; florfenicol; Microbiology; Pasteurella multocida; synergism; thiamphenicol

Potential synergism between florfenicol (FF) and thiamphenicol (TAP) was investigated for in vitro efficacy against Actinobacillus pleuropneumoniae and/or Pasteurella multocida as well as in vivo efficacy in swine. Among isolates of A. pleuropneumoniae (n = 58) and P. multocida (n = 79) from pigs in...