Metformin pre-treatment of stem cells from human exfoliated deciduous teeth promotes migration and angiogenesis of human umbilical vein endothelial cells for tissue engineering

• Published in: Cytotherapy (Oxford, England) Vol. 24; no. 11; pp. 1095 - 1104
• Main Authors: Deng, Shiwen, Lei, Tong, Chen, Hongyu, Zheng, Huiting, Xiao, Zhuangzhuang, Cai, Shanglin, Hang, Zhongci, Xiong, Weini, Yu, Yanqing, Zhang, Xiaoshuang, Yang, Yanjie, Bi, Wangyu, Du, Hongwu
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.11.2022
• Subjects: Advanced Basic Science; angiogenesis; metformin; Other; pre-treatment; SHED; metformin; SHED; pre-treatment; angiogenesis

Stem cells from human exfoliated deciduous teeth (SHED) play a significant role in tissue engineering and regenerative medicine. Angiogenesis is crucial in tissue regeneration and a primary target of regenerative medicine. As a first-line anti-diabetic drug, metformin demonstrates numerous valuable...