Endothelial angiopoietin-2 overexpression in explanted livers identifies subjects at higher risk of recurrence of hepatocellular carcinoma after liver transplantation

• Published in: Frontiers in oncology Vol. 12; p. 960808
• Main Authors: Lasagni, Simone, Leonardi, Filippo, Pivetti, Alessandra, Di Marco, Lorenza, Ravaioli, Federico, Serenari, Matteo, Gitto, Stefano, Critelli, Rosina Maria, Milosa, Fabiola, Romanzi, Adriana, Mancarella, Serena, Dituri, Francesco, Riefolo, Mattia, Catellani, Barbara, Magistri, Paolo, Romagnoli, Dante, Celsa, Ciro, Enea, Marco, de Maria, Nicola, Schepis, Filippo, Colecchia, Antonio, Cammà, Calogero, Cescon, Matteo, d’Errico, Antonietta, di Benedetto, Fabrizio, Giannelli, Gianluigi, Martinez-Chantar, Maria Luz, Villa, Erica
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 08.09.2022
• Subjects: angiopoietin-2; hepatocellular carcinoma; liver transplantation; neoangiogenesis; Oncology; recurrence; survival

Though the precise criteria for accessing LT are consistently being applied, HCC recurrence (HCC-R_LT) still affects more than 15% of the patients. We analyzed the clinical, histopathological, and biological features of patients with HCC to identify the predictive factors associated with cancer recu...