Increased tissue factor expression and poor nephroblastoma prognosis

• Published in: The Journal of urology Vol. 182; no. 4; p. 1594
• Main Authors: Maciel, Elinês O, Carvalhal, Gustavo F, da Silva, Vinícius D, Batista, Jr, Eraldo L, Garicochea, Bernardo
• Format: Journal Article
• Language: English
• Published: United States 01.10.2009
• Subjects: Child; Child, Preschool; Female; Humans; Immunohistochemistry; Infant; Kidney Neoplasms - chemistry; Kidney Neoplasms - metabolism; Kidney Neoplasms - mortality; Male; Prognosis; Survival Rate; Thromboplastin - analysis; Thromboplastin - biosynthesis; Wilms Tumor - chemistry; Wilms Tumor - metabolism; Wilms Tumor - mortality

There is potential interaction between malignant cell growth and the coagulation pathway. Recent studies suggest that tissue factor, a primary initiator of the extrinsic coagulation pathway, is expressed in various solid tumors in association with increased angiogenesis. To our knowledge we report f...