Is skeletal muscle oxidative capacity decreased in old age?
In humans, decreases in cardiac output play an important role in the age-related decrease in whole-body oxidative capacity. What remains less clear is whether a decline in skeletal muscle oxidative capacity is also an inevitable consequence of aging, as a number of other factors that could affect ox...
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Published in | Sports medicine (Auckland) Vol. 34; no. 4; pp. 221 - 229 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Chester
Adis International
01.01.2004
Hong Kong Wolters Kluwer Health, Inc Auckland |
Subjects | |
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Abstract | In humans, decreases in cardiac output play an important role in the age-related decrease in whole-body oxidative capacity. What remains less clear is whether a decline in skeletal muscle oxidative capacity is also an inevitable consequence of aging, as a number of other factors that could affect oxidative capacity also change with age, including: physical activity, health status, fibre-type composition, rates of protein synthesis and muscle blood supply. Both in vitro studies using muscle biopsy tissue and in vivo studies using 31P-magnetic resonance spectroscopy are used to study muscular oxidative capacity. Using these methodologies, researchers have found age-associated reductions in the oxidative capacities of specific muscles. In most cases, however, the influence of physical activity has not been adequately controlled, making it difficult to evaluate the effects of age itself from those of lifestyle changes associated with aging. Upon critical evaluation of the existing literature, the following picture regarding the effect of age on muscle oxidative capacity appears: although the maximum level of muscular oxidative capacity attainable through training may decline with age, much of the age-associated decline in oxidative function is related to the reductions in fitness and/or habitual physical activity that typically occur in this population. Future studies in this area must account for the health and activity status of their study participants. |
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AbstractList | In humans, decreases in cardiac output play an important role in the age-related decrease in whole-body oxidative capacity. What remains less clear is whether a decline in skeletal muscle oxidative capacity is also an inevitable consequence of aging, as a number of other factors that could affect oxidative capacity also change with age, including: physical activity, health status, fibre-type composition, rates of protein synthesis and muscle blood supply. Both in vitro studies using muscle biopsy tissue and in vivo studies using [sup.31]P-magnetic resonance spectroscopy are used to study muscular oxidative capacity. Using these methodologies, researchers have found age-associated reductions in the oxidative capacities of specific muscles. In most cases, however, the influence of physical activity has not been adequately controlled, making it difficult to evaluate the effects of age itself from those of lifestyle changes associated with aging. Upon critical evaluation of the existing literature, the following picture regarding the effect of age on muscle oxidative capacity appears: although the maximum level of muscular oxidative capacity attainable through training may decline with age, much of the age-associated decline in oxidative function is related to the reductions in fitness and/or habitual physical activity that typically occur in this population. Future studies in this area must account for the health and activity status of their study participants. In humans, decreases in cardiac output play an important role in the age-related decrease in whole-body oxidative capacity. What remains less clear is whether a decline in skeletal muscle oxidative capacity is also an inevitable consequence of aging, as a number of other factors that could affect oxidative capacity also change with age, including: physical activity, health status, fibre-type composition, rates of protein synthesis and muscle blood supply. Both in vitro studies using muscle biopsy tissue and in vivo studies using [sup.31]P-magnetic resonance spectroscopy are used to study muscular oxidative capacity. Using these methodologies, researchers have found age-associated reductions in the oxidative capacities of specific muscles. In most cases, however, the influence of physical activity has not been adequately controlled, making it difficult to evaluate the effects of age itself from those of lifestyle changes associated with aging. In humans, decreases in cardiac output play an important role in the age-related decrease in whole-body oxidative capacity. What remains less clear is whether a decline in skeletal muscle oxidative capacity is also an inevitable consequence of aging, as a number of other factors that could affect oxidative capacity also change with age, including: physical activity, health status, fibre-type composition, rates of protein synthesis and muscle blood supply. Both in vitro studies using muscle biopsy tissue and in vivo studies using 31P-magnetic resonance spectroscopy are used to study muscular oxidative capacity. Using these methodologies, researchers have found age-associated reductions in the oxidative capacities of specific muscles. In most cases, however, the influence of physical activity has not been adequately controlled, making it difficult to evaluate the effects of age itself from those of lifestyle changes associated with aging. Upon critical evaluation of the existing literature, the following picture regarding the effect of age on muscle oxidative capacity appears: although the maximum level of muscular oxidative capacity attainable through training may decline with age, much of the age-associated decline in oxidative function is related to the reductions in fitness and/or habitual physical activity that typically occur in this population. Future studies in this area must account for the health and activity status of their study participants. In humans, decreases in cardiac output play an important role in the age-related decrease in whole-body oxidative capacity. What remains less clear is whether a decline in skeletal muscle oxidative capacity is also an inevitable consequence of aging, as a number of other factors that could affect oxidative capacity also change with age, including: physical activity, health status, fibre-type composition, rates of protein synthesis and muscle blood supply. Both in vitro studies using muscle biopsy tissue and in vivo studies using super(31)P-magnetic resonance spectroscopy are used to study muscular oxidative capacity. Using these methodologies, researchers have found age-associated reductions in the oxidative capacities of specific muscles. In most cases, however, the influence of physical activity has not been adequately controlled, making it difficult to evaluate the effects of age itself from those of lifestyle changes associated with aging. Upon critical evaluation of the existing literature, the following picture regarding the effect of age on muscle oxidative capacity appears: although the maximum level of muscular oxidative capacity attainable through training may decline with age, much of the age-associated decline in oxidative function is related to the reductions in fitness and/or habitual physical activity that typically occur in this population. Future studies in this area must account for the health and activity status of their study participants. |
Audience | Professional Academic |
Author | RUSS, David W KENT-BRAUN, Jane A |
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Cites_doi | 10.1249/00005768-198708000-00015 10.1152/jappl.1993.75.2.573 10.1152/jappl.2001.90.5.1663 10.1152/ajpcell.1997.272.2.C638 10.1152/jappl.1997.82.1.63 10.1152/jappl.1982.53.6.1473 10.1152/ajpcell.2001.280.4.C782 10.1152/jn.1985.53.5.1303 10.1152/ajpcell.1997.272.2.C525 10.1002/1097-4598(200103)24:3<387::AID-MUS1010>3.0.CO;2-M 10.1152/jappl.1994.76.3.1247 10.1249/00003677-199500230-00012 10.1249/00003677-199800260-00012 10.1152/jappl.1989.66.6.2844 10.1111/j.1748-1716.1990.tb08975.x 10.1073/pnas.93.26.15364 10.1113/expphysiol.1998.sp004087 10.1073/pnas.82.24.8384 10.1152/jappl.1995.78.6.2033 10.1042/bj2910681 10.1152/jn.1965.28.3.560 10.1152/japplphysiol.01061.2002 10.1093/geronj/47.3.B71 10.1152/jappl.1999.86.6.2013 10.1093/qjmed/89.4.251 10.1006/abio.1997.2304 10.1006/bbrc.1996.1839 10.1097/00003677-200107000-00006 10.1073/pnas.77.12.7430 10.1002/mus.1202 10.1152/jappl.1993.75.5.2125 10.1152/jappl.1971.31.3.323 10.1016/S0531-5565(99)00077-7 10.1152/jappl.2000.89.3.1072 10.1139/y91-084 10.1152/jappl.1990.69.3.1165 10.1152/jappl.1993.75.2.813 10.1152/ajpcell.1988.254.4.C548 10.1152/jappl.1997.82.5.1411 10.1097/00004424-199902000-00004 10.1139/h93-031 10.1152/jappl.1998.85.4.1337 10.1007/s004210050446 10.1002/mrm.1910010303 10.1007/s004240100700 |
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References | 9696992 - Exerc Sport Sci Rev. 1998;26:253-85 8005869 - J Appl Physiol (1985). 1994 Mar;76(3):1247-55 10368368 - J Appl Physiol (1985). 1999 Jun;86(6):2013-8 3309542 - Med Sci Sports Exerc. 1987 Aug;19(4):410-20 9124295 - Am J Physiol. 1997 Feb;272(2 Pt 1):C525-34 9324953 - Anal Biochem. 1997 Oct 1;252(1):153-9 9951791 - Invest Radiol. 1999 Feb;34(2):116-25 12496142 - J Appl Physiol (1985). 2003 Apr;94(4):1479-84 5111849 - J Appl Physiol. 1971 Sep;31(3):323-5 8275050 - Can J Appl Physiol. 1993 Dec;18(4):366-78 9029199 - J Appl Physiol (1985). 1997 Jan;82(1):63-9 3354652 - Am J Physiol. 1988 Apr;254(4 Pt 1):C548-53 10705043 - Exp Gerontol. 2000 Feb;35(1):95-104 11474959 - Exerc Sport Sci Rev. 2001 Jul;29(3):118-23 8226454 - J Appl Physiol (1985). 1993 Aug;75(2):573-80 8307869 - J Appl Physiol (1985). 1993 Nov;75(5):2125-33 1650649 - Can J Physiol Pharmacol. 1991 May;69(5):576-80 1573181 - J Gerontol. 1992 May;47(3):B71-6 11245594 - Am J Physiol Cell Physiol. 2001 Apr;280(4):C782-8 10668196 - Histol Histopathol. 2000 Jan;15(1):61-71 8161485 - Magn Reson Q. 1994 Mar;10(1):43-63 6571561 - Magn Reson Med. 1984 Sep;1(3):307-15 11299253 - J Appl Physiol (1985). 2001 May;90(5):1663-70 10878112 - J Physiol. 2000 Jul 1;526 Pt 1:203-10 7556355 - Exerc Sport Sci Rev. 1995;23:305-47 9134886 - J Appl Physiol (1985). 1997 May;82(5):1411-5 9809848 - Eur J Appl Physiol Occup Physiol. 1998 Oct;78(5):460-5 2275405 - Acta Physiol Scand. 1990 Sep;140(1):55-62 10956353 - J Appl Physiol (1985). 2000 Sep;89(3):1072-8 2246165 - J Appl Physiol (1985). 1990 Sep;69(3):1165-70 3866229 - Proc Natl Acad Sci U S A. 1985 Dec;82(24):8384-8 9483424 - Exp Physiol. 1998 Jan;83(1):107-17 9124308 - Am J Physiol. 1997 Feb;272(2 Pt 1):C638-49 11745976 - Muscle Nerve. 2001 Dec;24(12):1665-76 8733511 - QJM. 1996 Apr;89(4):251-8 11353424 - Muscle Nerve. 2001 Mar;24(3):387-93 11692261 - Pflugers Arch. 2001 Oct;443(1):6-17 6938983 - Proc Natl Acad Sci U S A. 1980 Dec;77(12):7430-4 6218151 - J Appl Physiol Respir Environ Exerc Physiol. 1982 Dec;53(6):1473-80 8489495 - Biochem J. 1993 May 1;291 ( Pt 3):681-6 8226486 - J Appl Physiol (1985). 1993 Aug;75(2):813-9 8986817 - Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15364-9 7665396 - J Appl Physiol (1985). 1995 Jun;78(6):2033-8 2745349 - J Appl Physiol (1985). 1989 Jun;66(6):2844-9 14328454 - J Neurophysiol. 1965 May;28:560-80 8954933 - Biochem Biophys Res Commun. 1996 Dec 13;229(2):536-9 2987433 - J Neurophysiol. 1985 May;53(5):1303-22 9760325 - J Appl Physiol (1985). 1998 Oct;85(4):1337-41 Kent-Braun (R38-2-3713) 1993; 75 Short (R22-2-3713) 2001; 29 Meyer (R29-2-3713) 1988; 254 Gregory (R44-2-3713) 2001; 24 Chance (R24-2-3713) 1980; 77 Kent-Braun (R37-2-3713) 1990; 69 Barrientos (R16-2-3713) 1996; 229 Parizkova (R47-2-3713) 1971; 31 McCully (R6-2-3713) 1993; 75 Kent-Braun (R25-2-3713) 1995; 23 Staron (R10-2-3713) 1994; 76 Hook (R45-2-3713) 2001; 280 Kent-Braun (R2-2-3713) 2000; 89 Farley (R18-2-3713) 1998; 26 Chilibeck (R27-2-3713) 1998; 78 Schunk (R8-2-3713) 1999; 34 Meredith (R15-2-3713) 1989; 66 Walter (R34-2-3713) 1997; 272 Arnold (R32-2-3713) 1984; 1 Chilibeck (R48-2-3713) 1997; 82 Coggan (R3-2-3713) 1993; 75 Coggan (R4-2-3713) 1992; 47 Kemp (R33-2-3713) 1994; 10 Chance (R36-2-3713) 1985; 82 Larson-Meyer (R31-2-3713) 2001; 24 Pastoris (R12-2-3713) 2000; 35 Quistorff (R30-2-3713) 1992; 291 Jubrias (R40-2-3713) 2001; 90 Elder (R9-2-3713) 1982; 53 Brierley (R17-2-3713) 1996; 89 Henneman (R19-2-3713) 1965; 28 Proctor (R14-2-3713) 1995; 78 Larsson (R46-2-3713) 1997; 272 Proctor (R1-2-3713) 1997; 82 Houmard (R11-2-3713) 1998; 85 Rooyackers (R13-2-3713) 1996; 93 Bottinelli (R43-2-3713) 2001; 443 Zajac (R20-2-3713) 1985; 53 Klitgaard (R42-2-3713) 1990; 140 Rasmussen (R21-2-3713) 1997; 252 Haseler (R35-2-3713) 1999; 86 Marsh (R39-2-3713) 1993; 18 Kirkeby (R41-2-3713) 2000; 15 Sapega (R26-2-3713) 1987; 19 Welle (R23-2-3713) 2003; 94 McCully (R28-2-3713) 1991; 69 Chilibeck (R7-2-3713) 1998; 83 |
References_xml | – volume: 19 start-page: 410 year: 1987 ident: R26-2-3713 publication-title: Med Sci Sports Exerc doi: 10.1249/00005768-198708000-00015 contributor: fullname: Sapega – volume: 75 start-page: 573 year: 1993 ident: R38-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1993.75.2.573 contributor: fullname: Kent-Braun – volume: 90 start-page: 1663 year: 2001 ident: R40-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.2001.90.5.1663 contributor: fullname: Jubrias – volume: 272 start-page: C638 year: 1997 ident: R46-2-3713 publication-title: Am J Physiol doi: 10.1152/ajpcell.1997.272.2.C638 contributor: fullname: Larsson – volume: 82 start-page: 63 year: 1997 ident: R48-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1997.82.1.63 contributor: fullname: Chilibeck – volume: 53 start-page: 1473 year: 1982 ident: R9-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1982.53.6.1473 contributor: fullname: Elder – volume: 280 start-page: C782 year: 2001 ident: R45-2-3713 publication-title: Am J Physiol Cell Physiol doi: 10.1152/ajpcell.2001.280.4.C782 contributor: fullname: Hook – volume: 53 start-page: 1303 year: 1985 ident: R20-2-3713 publication-title: J Neurophysiol doi: 10.1152/jn.1985.53.5.1303 contributor: fullname: Zajac – volume: 272 start-page: C525 year: 1997 ident: R34-2-3713 publication-title: Am J Physiol doi: 10.1152/ajpcell.1997.272.2.C525 contributor: fullname: Walter – volume: 24 start-page: 387 year: 2001 ident: R44-2-3713 publication-title: Muscle Nerve doi: 10.1002/1097-4598(200103)24:3<387::AID-MUS1010>3.0.CO;2-M contributor: fullname: Gregory – volume: 76 start-page: 1247 year: 1994 ident: R10-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1994.76.3.1247 contributor: fullname: Staron – volume: 23 start-page: 305 year: 1995 ident: R25-2-3713 publication-title: Exerc Sport Sci Rev doi: 10.1249/00003677-199500230-00012 contributor: fullname: Kent-Braun – volume: 26 start-page: 253 year: 1998 ident: R18-2-3713 publication-title: Exerc Sport Sci Rev doi: 10.1249/00003677-199800260-00012 contributor: fullname: Farley – volume: 66 start-page: 2844 year: 1989 ident: R15-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1989.66.6.2844 contributor: fullname: Meredith – volume: 140 start-page: 55 year: 1990 ident: R42-2-3713 publication-title: Acta Physiol Scand doi: 10.1111/j.1748-1716.1990.tb08975.x contributor: fullname: Klitgaard – volume: 93 start-page: 15364 year: 1996 ident: R13-2-3713 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.93.26.15364 contributor: fullname: Rooyackers – volume: 10 start-page: 43 year: 1994 ident: R33-2-3713 publication-title: Magn Reson Q contributor: fullname: Kemp – volume: 83 start-page: 107 year: 1998 ident: R7-2-3713 publication-title: Exp Physiol doi: 10.1113/expphysiol.1998.sp004087 contributor: fullname: Chilibeck – volume: 82 start-page: 8384 year: 1985 ident: R36-2-3713 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.82.24.8384 contributor: fullname: Chance – volume: 78 start-page: 2033 year: 1995 ident: R14-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1995.78.6.2033 contributor: fullname: Proctor – volume: 291 start-page: 681 year: 1992 ident: R30-2-3713 publication-title: Biochem J doi: 10.1042/bj2910681 contributor: fullname: Quistorff – volume: 15 start-page: 61 year: 2000 ident: R41-2-3713 publication-title: Histol Histopathol contributor: fullname: Kirkeby – volume: 28 start-page: 560 year: 1965 ident: R19-2-3713 publication-title: J Neurophysiol doi: 10.1152/jn.1965.28.3.560 contributor: fullname: Henneman – volume: 94 start-page: 1479 year: 2003 ident: R23-2-3713 publication-title: J Appl Physiol doi: 10.1152/japplphysiol.01061.2002 contributor: fullname: Welle – volume: 47 start-page: B71 year: 1992 ident: R4-2-3713 publication-title: J Gerontol doi: 10.1093/geronj/47.3.B71 contributor: fullname: Coggan – volume: 86 start-page: 2013 year: 1999 ident: R35-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1999.86.6.2013 contributor: fullname: Haseler – volume: 89 start-page: 251 year: 1996 ident: R17-2-3713 publication-title: Q J Med doi: 10.1093/qjmed/89.4.251 contributor: fullname: Brierley – volume: 252 start-page: 153 year: 1997 ident: R21-2-3713 publication-title: Anal Biochem doi: 10.1006/abio.1997.2304 contributor: fullname: Rasmussen – volume: 229 start-page: 536 year: 1996 ident: R16-2-3713 publication-title: Biochem Biophys Res Commun doi: 10.1006/bbrc.1996.1839 contributor: fullname: Barrientos – volume: 29 start-page: 118 year: 2001 ident: R22-2-3713 publication-title: Exerc Sport Sci Rev doi: 10.1097/00003677-200107000-00006 contributor: fullname: Short – volume: 77 start-page: 7430 year: 1980 ident: R24-2-3713 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.77.12.7430 contributor: fullname: Chance – volume: 24 start-page: 1665 year: 2001 ident: R31-2-3713 publication-title: Muscle Nerve doi: 10.1002/mus.1202 contributor: fullname: Larson-Meyer – volume: 75 start-page: 2125 year: 1993 ident: R3-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1993.75.5.2125 contributor: fullname: Coggan – volume: 31 start-page: 323 year: 1971 ident: R47-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1971.31.3.323 contributor: fullname: Parizkova – volume: 35 start-page: 95 year: 2000 ident: R12-2-3713 publication-title: Exp Gerontol doi: 10.1016/S0531-5565(99)00077-7 contributor: fullname: Pastoris – volume: 89 start-page: 1072 year: 2000 ident: R2-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.2000.89.3.1072 contributor: fullname: Kent-Braun – volume: 69 start-page: 576 year: 1991 ident: R28-2-3713 publication-title: Can J Physiol Pharmacol doi: 10.1139/y91-084 contributor: fullname: McCully – volume: 69 start-page: 1165 year: 1990 ident: R37-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1990.69.3.1165 contributor: fullname: Kent-Braun – volume: 75 start-page: 813 year: 1993 ident: R6-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1993.75.2.813 contributor: fullname: McCully – volume: 254 start-page: C548 year: 1988 ident: R29-2-3713 publication-title: Am J Physiol doi: 10.1152/ajpcell.1988.254.4.C548 contributor: fullname: Meyer – volume: 82 start-page: 1411 year: 1997 ident: R1-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1997.82.5.1411 contributor: fullname: Proctor – volume: 34 start-page: 116 year: 1999 ident: R8-2-3713 publication-title: Invest Radiol doi: 10.1097/00004424-199902000-00004 contributor: fullname: Schunk – volume: 18 start-page: 366 year: 1993 ident: R39-2-3713 publication-title: Can J Appl Physiol doi: 10.1139/h93-031 contributor: fullname: Marsh – volume: 85 start-page: 1337 year: 1998 ident: R11-2-3713 publication-title: J Appl Physiol doi: 10.1152/jappl.1998.85.4.1337 contributor: fullname: Houmard – volume: 78 start-page: 460 year: 1998 ident: R27-2-3713 publication-title: Eur J Appl Physiol doi: 10.1007/s004210050446 contributor: fullname: Chilibeck – volume: 1 start-page: 307 year: 1984 ident: R32-2-3713 publication-title: Magn Reson Med doi: 10.1002/mrm.1910010303 contributor: fullname: Arnold – volume: 443 start-page: 6 year: 2001 ident: R43-2-3713 publication-title: Pflugers Arch doi: 10.1007/s004240100700 contributor: fullname: Bottinelli |
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SubjectTerms | Adult Aged Aged, 80 and over Aging - metabolism Biological and medical sciences Exercise Female Fundamental and applied biological sciences. Psychology Health aspects Humans Male Middle Aged Muscle, Skeletal - blood supply Muscle, Skeletal - metabolism Muscle, Skeletal - physiology Muscles Oxidative stress Oxygen - metabolism Physiological aspects Risk factors Striated muscle. Tendons Vertebrates: osteoarticular system, musculoskeletal system |
Title | Is skeletal muscle oxidative capacity decreased in old age? |
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