Targeted Arginine Metabolism Therapy: A Dilemma in Glioma Treatment

• Published in: Frontiers in oncology Vol. 12; p. 938847
• Main Authors: Hou, Xiaoshuang, Chen, Sui, Zhang, Po, Guo, Dongsheng, Wang, Baofeng
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 11.07.2022
• Subjects: arginine metabolism; glioma; metabolic reprogramming; Oncology; T lymphocytes; tumor microenvironment

Efforts in the treatment of glioma which is the most common primary malignant tumor of the central nervous system, have not shown satisfactory results despite a comprehensive treatment model that combines various treatment methods, including immunotherapy. Cellular metabolism is a determinant of the...