Routes of abuse of prescription opioid analgesics: a review and assessment of the potential impact of abuse-deterrent formulations

• Published in: Postgraduate medicine Vol. 128; no. 1; p. 85
• Main Authors: Gasior, Maciej, Bond, Mary, Malamut, Richard
• Format: Journal Article
• Language: English
• Published: England 02.01.2016
• Subjects: Analgesics, Opioid - administration & dosage; Analgesics, Opioid - therapeutic use; Chemistry, Pharmaceutical; Chronic Pain - drug therapy; Delayed-Action Preparations; Drug Administration Routes; Humans; Opioid-Related Disorders - etiology; Opioid-Related Disorders - prevention & control; United States; United States Food and Drug Administration; United States; Prescription opioid analgesics; abuse-deterrent formulation; abuse; manipulation; route of administration

Prescription opioid analgesics are an important treatment option for patients with chronic pain; however, misuse, abuse and diversion of these medications are a major global public health concern. Prescription opioid analgesics can be abused via intended and non-intended routes of administration, bo...