Mito‐Bomb: Targeting Mitochondria for Cancer Therapy

• Published in: Advanced materials (Weinheim) Vol. 33; no. 43; pp. e2007778 - n/a
• Main Authors: Guo, Xiaolu, Yang, Naidi, Ji, Wenhui, Zhang, Hang, Dong, Xiao, Zhou, Zhiqiang, Li, Lin, Shen, Han‐Ming, Yao, Shao Q., Huang, Wei
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.10.2021
• Subjects: Animals; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Apoptosis; Cancer; Cancer therapies; cancer therapy; chemodynamic therapy; Coordination compounds; Humans; Hyperthermia; Mitochondria; Mitochondria - drug effects; Mitochondria - metabolism; Neoplasms - drug therapy; Neoplasms - metabolism; Neoplasms - pathology; Organelles; Peptides; Phosphines; Photochemotherapy - methods; Photodynamic therapy; photothermal therapy; Radiation therapy; Selectivity; Side effects; Toxicity; cancer therapy; chemodynamic therapy; mitochondria; photodynamic therapy; photothermal therapy

Cancer has been one of the most common life‐threatening diseases for a long time. Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) have limited effects due to drug resistance, unsatisfactory treatment efficiency, and side effects. In recent years, photodynamic t...