Rhodium‐Catalyzed Dynamic Kinetic Asymmetric Hydrosilylation to Access Silicon‐Stereogenic Center

• Published in: Angewandte Chemie International Edition Vol. 61; no. 51; pp. e202214147 - n/a
• Main Authors: Zeng, Yan, Fang, Xiao‐Jun, Tang, Ren‐He, Xie, Jing‐Yu, Zhang, Feng‐Jiao, Xu, Zheng, Nie, Yi‐Xue, Xu, Li‐Wen
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 19.12.2022; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: Asymmetric Catalysis; Asymmetry; Catalysts; Chemistry; Chemistry, Multidisciplinary; Chirality; Chloride ions; Density functional theory; Dynamic Kinetic Resolution; Enantiomers; Hydrosilylation; Ligands; Organosilicon; Organosilicon compounds; Phosphine; Phosphines; Physical Sciences; Rhodium; Science & Technology; Silacycle; Silicon; Silicon-Stereogenic; Substitution reactions; Substrates; Dynamic Kinetic Resolution; PHOSPHORUS; Asymmetric Catalysis; HYDROGENATION; ENANTIOSELECTIVITY; Silacycle; SILANES; CONSTRUCTION; Organosilicon; LIGAND; Silicon-Stereogenic; C-H SILYLATION

Strategies on the construction of enantiomerically pure silicon‐stereogenic silanes generally relies on desymmetrization of prochiral and symmetric substrates. However, dynamic kinetic asymmetric transformations of organosilicon compounds have remained underdeveloped and unforeseen owing to a lack o...