Iterative Synthesis of 2‐Deoxyoligosaccharides Enabled by Stereoselective Visible‐Light‐Promoted Glycosylation

• Published in: Angewandte Chemie International Edition Vol. 61; no. 20; pp. e202114726 - n/a
• Main Authors: Liu, Kai‐Meng, Wang, Peng‐Yu, Guo, Zhen‐Yan, Xiong, De‐Cai, Qin, Xian‐Jin, Liu, Miao, Liu, Meng, Xue, Wan‐Ying, Ye, Xin‐Shan
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 09.05.2022; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: 2-Deoxyglycosides; Alcohols; Alcohols - chemistry; Alkenes; Alkenes - chemistry; Bromine Radical; Chemistry; Chemistry, Multidisciplinary; Digoxin; Glycosylation; Intermolecular Hydroetherification; Light; Linkages; Photoreaction; Physical Sciences; Science & Technology; Stereoselectivity; Substrates; Synthesis; Stereoselectivity; ALCOHOL; DEOXYGLYCOSIDES; REACTIVITY; 2-Deoxyglycosides; Intermolecular Hydroetherification; Bromine Radical; Photoreaction; 2-DEOXY-BETA-GLYCOSIDES

The photoinitiated intramolecular hydroetherification of alkenols has been used to form C−O bonds, but the intermolecular hydroetherification of alkenes with alcohols remains an unsolved challenge. We herein report the visible‐light‐promoted 2‐deoxyglycosylation of alcohols with glycals. The glycosy...