Interest of hair tests to discriminate a tail end of a doping regimen from a possible contamination in case of challenging an anti‐doping rule violation. V. Case reports involving trimetazidine, a drug where the concentration after a single 20 mg dose has been established

• Published in: Drug testing and analysis Vol. 17; no. 6; pp. 779 - 785
• Main Authors: Kintz, Pascal, Ameline, Alice, Gheddar, Laurie
• Format: Journal Article
• Language: English
• Published: England 01.06.2025
• Subjects: Chromatography, Liquid - methods; contamination; doping; Doping in Sports; hair; Hair - chemistry; Humans; Male; single dose; Substance Abuse Detection - methods; Tandem Mass Spectrometry - methods; trimetazidine; Trimetazidine - administration & dosage; Trimetazidine - analysis; Trimetazidine - urine; Vasodilator Agents - administration & dosage; Vasodilator Agents - analysis; Vasodilator Agents - urine; doping; hair; trimetazidine; single dose; contamination

The identification of trimetazidine, a medicine used for treating stable angina pectoris and for preventing angina attacks, has been recently observed in doping cases involving high profile athletes from various countries over the world. In all the files where the authors have been involved, the uri...