Osteogenesis imperfecta: changes in noncollagenous proteins in bone

• Published in: Journal of bone and mineral research Vol. 6; no. 5; p. 501
• Main Authors: Vetter, U, Fisher, L W, Mintz, K P, Kopp, J B, Tuross, N, Termine, J D, Robey, P G
• Format: Journal Article
• Language: English
• Published: United States 01.05.1991
• Subjects: Adolescent; alpha-2-HS-Glycoprotein; Amino Acids - analysis; Blood Proteins - metabolism; Bone and Bones - metabolism; Bone Density; Child; Child, Preschool; Decorin; Extracellular Matrix Proteins; Humans; Infant; Osteocalcin - metabolism; Osteogenesis Imperfecta - metabolism; Osteonectin - metabolism; Proteins - metabolism; Proteoglycans - metabolism; Sialoglycoproteins - metabolism

The noncollagenous proteins osteonectin, bone sialoprotein, osteocalcin, the small proteoglycan decorin (PG II), and alpha 2-HS glycoprotein (which is synthesized in the liver but highly concentrated in bone) were measured in extracts of cortical bone from 3 type I, 2 type II, 8 type III and 13 type...