Relationship between cardiorespiratory phase coherence during hypoxia and genetic polymorphism in humans

• Published in: The Journal of physiology Vol. 598; no. 10; pp. 2001 - 2019
• Main Authors: Lancaster, Gemma, Debevec, Tadej, Millet, Gregoire P., Poussel, Mathias, Willis, Sarah J., Mramor, Minca, Goričar, Katja, Osredkar, Damjan, Dolžan, Vita, Stefanovska, Aneta
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.05.2020; John Wiley and Sons Inc
• Subjects: Altitude; Altitude Sickness; Apnea; Blood flow; cardiovascular dynamics; CAT; EKG; Gene polymorphism; Genetic factors; Heart rate; heart rate variability; Humans; Hyperventilation; Hypoxia; Hypoxia - genetics; Microvasculature; NOTCH4; periodic breathing; Polymorphism; Polymorphism, Genetic; Research Paper; Respiration; Respiratory; wavelet analysis; hypoxia; heart rate variability; wavelet analysis; NOTCH4; cardiovascular dynamics; CAT; periodic breathing

Key points High altitude‐induced hypoxia in humans evokes a pattern of breathing known as periodic breathing (PB), in which the regular oscillations corresponding to rhythmic expiration and inspiration are modulated by slow periodic oscillations. The phase coherence between instantaneous heart rate...