An adenine-to-guanine nucleotide change in the IRES SL-IV domain of picornavirus/hepatitis C chimeric viruses leads to a nonviable phenotype - McKnight, Kevin L; Sandefur, Stephanie; Phipps, Krista M; Heinz, Beverly A (Virology (New York, N.Y.), 2003)
Keywords: Adenine - chemistry; Animals; Base Sequence; Cattle; Chimeric viruses; Gene Expression Regulation, Viral; Guanine - chemistry; HeLa Cells; Hepacivirus - chemistry; Hepacivirus - genetics; Hepacivirus - physiology; Hepatitis C virus; Humans; Internal ribosomal entry site; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Picornaviridae - chemistry; Picornaviridae - genetics; Picornaviridae - physiology; Poliovirus - chemistry; Poliovirus - genetics; Poliovirus - physiology; Protein Biosynthesis; Recombination, Genetic; Ribosomes - metabolism; RNA structure; RNA, Viral - chemistry; RNA, Viral - genetics; Transcription, Genetic; Transfection; Translation; Viral Plaque Assay; Internal ribosomal entry site; Translation; Hepatitis C virus; RNA structure; Chimeric viruses