Novel Advances in Cell-Free Therapy for Premature Ovarian Failure (POF): A Comprehensive Review

• Published in: Advanced pharmaceutical bulletin Vol. 14; no. 3; pp. 543 - 557
• Main Authors: Yahyavi, Yahya, Kheradi, Niloufar, Karimi, Abbas, Ebrahimi-Kalan, Abbas, Ramezani, Fatemeh, Yousefi, Soudabe, Teymouri Nobari, Shirin, Sadrekarimi, Hourieh, Nouri, Mohammad, Edalati, Mahdi
• Format: Journal Article
• Language: English
• Published: Iran Tabriz University of Medical Sciences 01.10.2024
• Subjects: Apoptosis; Autoimmune diseases; Blood platelets; exosome therapy; Females; Fertility; Genetic counseling; Growth factors; Hormone replacement therapy; Iatrogenesis; in vitro activation; Infertility; Medical research; Medicine; MicroRNAs; mitochondrial targeting therapies; Ovaries; Ovulation; plt-exos; prp; Reproductive health; Review; stem cell therapy; Stem cells; Surgery; theca cells signaling pathways; Thyroid gland; Womens health; Exosome therapy; Theca cells signaling pathways; PLT-Exos; In vitro activation; Stem cell therapy; Mitochondrial targeting therapies; PRP

Premature ovarian failure (POF), is a condition characterized by the early decline of ovulation function. POF is a complex disorder that can be caused by various factors, and the idiopathic form represents a significant proportion of POF patients. Hormone replacement therapy (HRT) is currently consi...