Antimicrobial activity of a quaternary ammonium methacryloxy silicate-containing acrylic resin: a randomised clinical trial

• Published in: Scientific reports Vol. 6; no. 1; p. 21882
• Main Authors: Liu, Si-ying, Tonggu, Lige, Niu, Li-na, Gong, Shi-qiang, Fan, Bing, Wang, Liguo, Zhao, Ji-hong, Huang, Cui, Pashley, David H., Tay, Franklin R.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 23.02.2016; Nature Publishing Group
• Subjects: 631/326/46; 692/700/459/1748; Acrylic Resins - pharmacology; Actinomyces - drug effects; Actinomyces - growth & development; Adult; Ammonium; Anti-Infective Agents - pharmacology; Antimicrobial activity; Antimicrobial agents; Biofilms; Biofilms - drug effects; Biofilms - growth & development; Candida albicans - drug effects; Candida albicans - growth & development; Clinical trials; Confocal microscopy; Dentures; Double-Blind Method; Female; Fusobacterium - drug effects; Fusobacterium - growth & development; Humanities and Social Sciences; Humans; Male; Methacrylates - pharmacology; Microbial Viability - drug effects; Microscopy, Confocal; Middle Aged; Mucosa; multidisciplinary; Orthodontic Retainers - microbiology; Orthodontics; Quaternary Ammonium Compounds - pharmacology; Science; Science (multidisciplinary); Streptococcus - drug effects; Streptococcus - growth & development

Quaternary ammonium methacryloxy silicate (QAMS)-containing acrylic resin demonstrated contact-killing antimicrobial ability in vitro after three months of water storage. The objective of the present double-blind randomised clinical trial was to determine the in vivo antimicrobial efficacy of QAMS-c...