Pathogenesis and treatment of nasopharyngeal carcinoma

• Published in: Seminars in oncology Vol. 31; no. 6; p. 794
• Main Authors: Chan, Anthony T C, Teo, Peter M L, Huang, Dolly P
• Format: Journal Article
• Language: English
• Published: United States 01.12.2004
• Subjects: Chemotherapy, Adjuvant; Combined Modality Therapy; Humans; Nasopharyngeal Neoplasms - etiology; Nasopharyngeal Neoplasms - genetics; Nasopharyngeal Neoplasms - therapy

Nasopharyngeal carcinoma (NPC), an endemic tumor in southern China, has three unique etiologic factors, including genetic susceptibility, chemical carcinogens, and association with Epstein-Barr virus (EBV) infection. Recent identification of critical genetic changes in this cancer has allowed the de...