Evolutionary conservation analysis between the essential and nonessential genes in bacterial genomes

• Published in: Scientific reports Vol. 5; no. 1; p. 13210
• Main Authors: Luo, Hao, Gao, Feng, Lin, Yan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 14.08.2015; Nature Publishing Group
• Subjects: 631/114/2164; 631/326/41/2529; Bacteria; Bacterial Proteins - genetics; Base Sequence; Carbohydrate metabolism; Chromosome Mapping - methods; Conserved Sequence - genetics; Evolution, Molecular; Evolutionary conservation; Experimental methods; Genes, Bacterial - genetics; Genes, Essential - genetics; Genome, Bacterial - genetics; Genomes; Humanities and Social Sciences; Lipid metabolism; Metabolism; Molecular Sequence Data; multidisciplinary; Natural selection; Recombination; Science; Transcription

Essential genes are thought to be critical for the survival of the organisms under certain circumstances and the natural selection acting on essential genes is expected to be stricter than on nonessential ones. Up to now, essential genes have been identified in approximately thirty bacterial organis...