Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism

• Published in: Scientific reports Vol. 6; no. 1; p. 31281
• Main Authors: Lea, Richard G., Byers, Andrew S., Sumner, Rebecca N., Rhind, Stewart M., Zhang, Zulin, Freeman, Sarah L., Moxon, Rachel, Richardson, Holly M., Green, Martin, Craigon, Jim, England, Gary C. W.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 09.08.2016; Nature Publishing Group
• Subjects: 13/106; 14; 631/136/1425; 631/601/1737; 692/699/2732/1577; Animals; Biphenyl; Chemicals; Cryptorchidism; Deoxyribonucleic acid; Diethylhexyl Phthalate - chemistry; DNA; Dogs; Environmental Exposure; Explants; Female; Food; Humanities and Social Sciences; Infants; Male; Motility; multidisciplinary; Offspring; PCB; Polychlorinated biphenyls; Polychlorinated Biphenyls - chemistry; Reproduction - drug effects; Science; Secretion; Semen; Semen - drug effects; Semen Analysis; Sperm; Sperm Motility - drug effects; Spermatozoa - drug effects; Testes; Testis - drug effects; Testosterone; Testosterone - metabolism

Adverse temporal trends in human semen quality and cryptorchidism in infants have been associated with exposure to environmental chemicals (ECs) during development. Here we report that a population of breeding dogs exhibit a 26 year (1988–2014) decline in sperm quality and a concurrent increased inc...