Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons - Sapio, Matthew R.; Neubert, John K.; LaPaglia, Danielle M.; Maric, Dragan; Keller, Jason M.; Raithel, Stephen J.; Rohrs, Eric L.; Anderson, Ethan M.; Butman, John A.; Caudle, Robert M.; Brown, Dorothy C.; Heiss, John D.; et al. (The Journal of clinical investigation, 2018)
Keywords: Analgesics, Non-Narcotic - pharmacology; Animals; Axotomy; Cancer Pain - drug therapy; Cancer Pain - metabolism; Cancer Pain - pathology; Diterpenes - pharmacology; Dogs; Ganglia, Spinal - metabolism; Ganglia, Spinal - pathology; Humans; Pain Management; Rats; Sensory Receptor Cells - metabolism; Sensory Receptor Cells - pathology; TRPV Cation Channels; Neuroscience; Expression profiling; Pain; Addiction; Clinical Trials