European consensus-based recommendations for diagnosis and treatment of immunoglobulin A vasculitis—the SHARE initiative

• Published in: Rheumatology (Oxford, England) Vol. 58; no. 9; pp. 1607 - 1616
• Main Authors: Ozen, Seza, Marks, Stephen D., Brogan, Paul, Groot, Noortje, de Graeff, Nienke, Avcin, Tadej, Bader-Meunier, Brigitte, Dolezalova, Pavla, Feldman, Brian M., Kone-Paut, Isabelle, Lahdenne, Pekka, McCann, Liza, Pilkington, Clarissa, Ravelli, Angelo, van Royen, Annet, Uziel, Yosef, Vastert, Bas, Wulffraat, Nico, Kamphuis, Sylvia, Beresford, Michael W.
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.09.2019; Oxford Publishing Limited (England)
• Subjects: Analgesia; Analgesia - methods; Angiotensin-converting enzyme inhibitors; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Biopsy; Child; Children; Diagnosis; Enzymes; Evidence-Based Medicine - methods; Gastrointestinal Diseases - diagnosis; Gastrointestinal Diseases - etiology; Glomerulonephritis, IGA - diagnosis; Glomerulonephritis, IGA - drug therapy; Glomerulonephritis, IGA - etiology; Glomerulonephritis, IGA - pathology; Glucocorticoids - therapeutic use; Humans; Immunoglobulin A; Immunoglobulin A - analysis; Kidney - pathology; Kidneys; Literature reviews; Medical diagnosis; Nephritis; Pain perception; Pediatrics; Peptidyl-dipeptidase A; Purpura, Schoenlein-Henoch - complications; Purpura, Schoenlein-Henoch - diagnosis; Purpura, Schoenlein-Henoch - drug therapy; Purpura, Schoenlein-Henoch - pathology; Rheumatology; Schonlein-Henoch purpura; Severity of Illness Index; Skin - pathology; Systemic vasculitis; systemic vasculitis; childhood/paediatric; diagnosis; IgA vasculitis (Henoch–Schönlein purpura); management; recommendations

Abstract Objectives IgA vasculitis (IgAV, formerly known as Henoch–Schönlein purpura) is the most common cause of systemic vasculitis in childhood. To date, there are no internationally agreed, evidence-based guidelines concerning the appropriate diagnosis and treatment of IgAV in children. Accordin...